Results 21 to 30 of about 7,795,985 (403)
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Genome Biology, 2009 Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of ...
Ben Langmead +3 more
semanticscholar +1 more source
MODELTEST: testing the model of DNA substitution
Bioinform., 1998 SUMMARY The program MODELTEST uses log likelihood scores to establish the model of DNA evolution that best fits the data. AVAILABILITY The MODELTEST package, including the source code and some documentation is available at http://bioag.byu. edu/zoology/
D. Posada, K. Crandall
semanticscholar +1 more source
DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis. [PDF]
, 2016 The abundant Fis nucleoid protein selectively binds poorly related DNA sequences with high affinities to regulate diverse DNA reactions. Fis binds DNA primarily through DNA backbone contacts and selects target sites by reading conformational properties ...
Cascio, Duilio +3 more
core +6 more sources
BMC Plant Biology, 2021 Bacterial canker of tomato (Solanum lycopersicon) caused by the Gram-positive bacterium Clavibacter michiganensis subsp. michiganensis (Cmm) is an economically important disease.
Naoki Yokotani +8 more
doaj +1 more source
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Nature, 2016 Current genome-editing technologies introduce double-stranded (ds) DNA breaks at a target locus as the first step to gene correction. Although most genetic diseases arise from point mutations, current approaches to point mutation correction are ...
Alexis C. Komor +4 more
semanticscholar +1 more source
Mechanisms of Zika virus infection and neuropathogenesis [PDF]
, 2016 A spotlight has been focused on the mosquito-borne Zika virus (ZIKV) because of its epidemic outbreak in Brazil and Latin America, as well as the severe neurological manifestations of microcephaly and Guillain–Barré syndrome associated with infection. In
Coyne, Carolyn B +4 more
core +2 more sources
Scientific Reports, 2022 Carrot is a major source of provitamin A in a human diet. Two of the most important traits for carrot breeding are carotenoid contents and root color.
Taeko Shibaya +8 more
doaj +1 more source
DNA sequencing with chain-terminating inhibitors.
Proceedings of the National Academy of Sciences of the United States of America, 1977 A new method for determining nucleotide sequences in DNA is described. It is similar to the "plus and minus" method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol.
F. Sanger, S. Nicklen, A. Coulson
semanticscholar +1 more source
Production of human recombinant proapolipoprotein A-I in Escherichia coli: purification and biochemical characterization [PDF]
, 1989 A human liver cDNA library was used to isolate a clone coding for apolipoprotein A-I (Apo A-I). The clone carries the sequence for the prepeptide (18 amino acids), the propeptide (6 amino acids), and the mature protein (243 amino acids).
Bollen, A. +12 more
core +1 more source
Impact of self-association on the architectural properties of bacterial nucleoid proteins [PDF]
Biophysical Journal, 120 (2021) 370-378, 2021 The chromosomal DNA of bacteria is folded into a compact body called the nucleoid, which is composed essentially of DNA (80%), RNA (10%), and a number of different proteins (10%). These nucleoid proteins act as regulators of gene expression and influence the organization of the nucleoid by bridging, bending, or wrapping the DNA.
arxiv +1 more source