Results 31 to 40 of about 7,795,985 (403)

DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

open access: yesBioinform., 2009
MOTIVATION DnaSP is a software package for a comprehensive analysis of DNA polymorphism data. Version 5 implements a number of new features and analytical methods allowing extensive DNA polymorphism analyses on large datasets.
P. Librado, J. Rozas
semanticscholar   +1 more source

Self-replication and evolution of DNA crystals [PDF]

open access: yes, 2005
Is it possible to create a simple physical system that is capable of replicating itself? Can such a system evolve interesting behaviors, thus allowing it to adapt to a wide range of environments?
A.G. Cairns-Smith   +16 more
core   +2 more sources

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

open access: yesScience, 2012
Ditching Invading DNA Bacteria and archaea protect themselves from invasive foreign nucleic acids through an RNA-mediated adaptive immune system called CRISPR (clustered regularly interspaced short palindromic repeats)/CRISPR-associated (Cas).
M. Jinek   +5 more
semanticscholar   +1 more source

A record of the Porbeagle, Lamna nasus, in coastal waters of Buenos Aires (Argentina) confirmed by DNA barcoding [PDF]

open access: yes, 2015
A record of a juvenile Porbeagle, Lamna nasus, in the coastal waters of Argentina is confirmed by DNA barcoding, since the specimen lacked some external diagnostic features.
Díaz de Astarloa, Juan Martín   +2 more
core   +1 more source

DNA methylation age of human tissues and cell types

open access: yesGenome Biology, 2013
It is not yet known whether DNA methylation levels can be used to accurately predict age across a broad spectrum of human tissues and cell types, nor whether the resulting age prediction is a biologically meaningful measure.
S. Horvath
semanticscholar   +1 more source

Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

open access: yesNature Communications, 2020
The RNase activity of Inositol-Requiring Enzyme 1 (IRE1) can be allosterically regulated by ATP-competitive inhibitors of the IRE1 kinase domain. Here, the authors identify ATP-competitive IRE1 RNase activators with improved selectivity and cellular ...
Elena Ferri   +17 more
doaj   +1 more source

An Integrated Encyclopedia of DNA Elements in the Human Genome

open access: yesNature, 2012
The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor
ENCODEConsortium, Martin Renqiang Min
semanticscholar   +1 more source

Cohesin causes replicative DNA damage by trapping DNA topological stress [PDF]

open access: yes, 2020
DNA topological stress inhibits DNA replication fork (RF) progression and contributes to DNA replication stress. In Saccharomyces cerevisiae, we demonstrate that centromeric DNA and the rDNA array are especially vulnerable to DNA topological stress ...
Baxter, Jonathan   +2 more
core   +1 more source

Breaking DNA

open access: yesScience, 2016
A long-sought protein that helps to break DNA is finally discovered [Also see Research Articles by Vrielynck et al. and Robert et al. ]
Claeys Bouuaert, Corentin, Keeney, Scott
openaire   +4 more sources

Author Correction: Artificial neural network, predictor variables and sensitivity threshold for DNA methylation-based age prediction using blood samples

open access: yesScientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Zhonghui Thong   +5 more
doaj   +1 more source

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