Results 31 to 40 of about 6,778,475 (339)
Molecular Therapy: Methods & Clinical Development, 2021 CRISPR systems enable targeted genome editing in a wide variety of organisms by introducing single- or double-strand DNA breaks, which are repaired using endogenous molecular pathways.
Gavin Kurgan +13 more
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FlavonoidSearch: A system for comprehensive flavonoid annotation by mass spectrometry
Scientific Reports, 2017 Currently, in mass spectrometry-based metabolomics, limited reference mass spectra are available for flavonoid identification. In the present study, a database of probable mass fragments for 6,867 known flavonoids (FsDatabase) was manually constructed ...
Nayumi Akimoto +10 more
doaj +1 more source
Scientific Reports, 2021 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Zhonghui Thong +5 more
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DNA supercoiling inhibits DNA knotting [PDF]
Nucleic Acids Research, 2008 Despite the fact that in living cells DNA molecules are long and highly crowded, they are rarely knotted. DNA knotting interferes with the normal functioning of the DNA and, therefore, molecular mechanisms evolved that maintain the knotting and catenation level below that which would be achieved if the DNA segments could pass randomly through each ...
Burnier Y, Dorier J, Stasiak A
openaire +4 more sources
Scanning Electrochemical Microscopy of DNA Monolayers Modified with Nile Blue [PDF]
, 2008 Scanning electrochemical microscopy (SECM) is used to probe long-range charge transport (CT) through DNA monolayers containing the redox-active Nile Blue (NB) intercalator covalently affixed at a specific location in the DNA film. At substrate potentials
Barton, Jacqueline K. +4 more
core +2 more sources
DNA-coated Functional Oil Droplets
, 2017 Many industrial soft materials often include oil-in-water (O/W) emulsions at the core of their formulations. By using tuneable interface stabilizing agents, such emulsions can self-assemble into complex structures.
Bruns, Nico +8 more
core +2 more sources
, 2011 DNA-DNA hybridization (DDH) techniques have been used as the gold standard for the genomic similarity analyses of pair-wise sets of strains for classification purposes. The method has had an enormous relevance during the last half a century of classification of prokaryotes.
Rosselló-Mora, Ramón +2 more
openaire +2 more sources
Length-independent DNA packing into nanopore zero-mode waveguides for low-input DNA sequencing [PDF]
, 2017 Compared with conventional methods, single-molecule real-time (SMRT) DNA sequencing exhibits longer read lengths than conventional methods, less GC bias, and the ability to read DNA base modifications.
Henley, Robert Y. +4 more
core +1 more source
DNA knots and DNA supercoiling [PDF]
Cell Cycle, 2011 Keywords: DNA topoisomerases; DNA topology; DNA structure Reference EPFL-ARTICLE-167094doi:10.4161/cc.10.9.15293View record in Web of Science Record created on 2011-06-24, modified on 2017-05 ...
Guillaume, Witz +2 more
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High cell-surface density of HER2 deforms cell membranes
Nature Communications, 2016 HER2 is frequently overexpressed in breast cancer in association with increased metastatic potential. Here, the authors show that HER2 overexpression causes deformation of cell membranes in a signalling-independent manner that contributes to the disease ...
Inhee Chung +8 more
doaj +1 more source