Results 51 to 60 of about 2,098,704 (336)

Using DNA barcoding to improve invasive pest identification at U.S. ports-of-entry

PLoS ONE, 2019
Interception of potential invasive species at ports-of-entry is essential for effective biosecurity and biosurveillance programs. However, taxonomic assessment of the immature stages of most arthropods is challenging; characters for identification are ...
Mary J L Madden, Robert G. Young, John W. Brown, S. Miller, A. Frewin, R. Hanner   +5 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Reliable DNA barcoding performance proved for species and island populations of comoran squamate reptiles. [PDF]

PLoS ONE, 2013
In the past decade, DNA barcoding became increasingly common as a method for species identification in biodiversity inventories and related studies.
Oliver Hawlitschek, Zoltán T Nagy, Johannes Berger, Frank Glaw   +3 more
doaj   +1 more source

The Expanding Role of DNA Barcodes: Indispensable Tools for Ecology, Evolution, and Conservation

Diversity, 2022
DNA barcoding has transformed the fields of ecology, evolution, and conservation by providing a rapid and effective tool for species identification.
Morgan R. Gostel, W. John Kress
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Progress in the use of DNA barcodes in the identification and classification of medicinal plants

Ecotoxicology and Environmental Safety, 2021
DNA barcoding is an emerging molecular identification and classification technology that has been applied to medicinal plants since 2008. The application of this technique has greatly ensured the safety and effectiveness of medicinal materials.
Jie Yu, Xi Wu, Chang Liu, Steve Newmaster, Subramanyam Ragupathy, W. John Kress   +5 more
doaj   +1 more source

DNA-BAR: distinguisher selection for DNA barcoding [PDF]

Bioinformatics, 2005
DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism.
B, DasGupta, K M, Konwar, I I, Mandoiu, A A, Shvartsman   +3 more
openaire   +2 more sources

DNA Barcoding: Error Rates Based on Comprehensive Sampling

PLoS Biology, 2005
DNA barcoding has attracted attention with promises to aid in species identification and discovery; however, few well-sampled datasets are available to test its performance.
Christopher P. Meyer, Gustav Paulay
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Sustainable tourism and green space: exploring how green spaces and natural attractions contribute to local tourism economies and revenue generation in Gauteng province

Discover Sustainability
Green spaces and natural attractions are critical assets in promoting sustainable tourism, particularly in ecologically diverse regions such as South Africa.
Enioluwa Jonathan Ijatuyi, Kowiyou Yessoufou, Hosea Olayiwola Patrick   +2 more
doaj   +1 more source