Results 281 to 290 of about 108,714 (328)

Optimized CRISPR-Cas9 system for efficient engineering of ecDNA in cancer cells. [PDF]

open access: yesNucleic Acids Res
Sugimoto Y   +7 more
europepmc   +1 more source

Mechanistic Insights Into NFIX‐Mediated DNA Recognition and Transcriptional Regulation in Skeletal Muscle

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
An atomic view of the NFIX–DNA complex reveals recognition of the TGGCA motif and links sequence‐specific binding to the transcriptional programs governing skeletal muscle development and disease. ABSTRACT Skeletal muscle is essential for voluntary movement and exhibits a remarkable capacity for regeneration following injury.
Ci Zhu   +11 more
wiley   +1 more source

Detection of Cancer‐Associated Mutations Using Primer Exchange Reaction‐Based Signal Amplification and Lateral Flow Assays

open access: yesSmall Science, Volume 6, Issue 2, February 2026.
This article presents the detection of cancer‐specific mutations using primer exchange reaction‐based signal amplification on lateral flow assays. This approach enables sensitive detection of clinically relevant mutations, including PIK3CA E545K/A and TP53 R280K, from RNA isolated from breast cancer cell lines and from RNA derived from circulating ...
Samet Kocabey, Curzio Rüegg
wiley   +1 more source

Genome-Wide DNA Methylation Analysis of Performance Variation in the 5000-m Speed Race of Yili Horses. [PDF]

open access: yesAnimals (Basel)
Shan D   +9 more
europepmc   +1 more source

Microbial Metabolism and Disease Virulence Changes Across Day and Night in Coral Black Band Disease Lesions

open access: yesEnvironmental Microbiology, Volume 28, Issue 2, February 2026.
Metatranscriptomic reads from black band disease (BBD) lesions derived from samples collected during the day and night were mapped to near‐complete BBD‐derived metagenome‐assembled genomes to profile diurnal metabolic shifts among key microbial groups. Photosynthesis genes from the cyanobacterium Roseofilum reptotaenium were highly expressed during the
Julia Y. Hung   +4 more
wiley   +1 more source

Evaluation of p53 Gene Mutations in Oral Lichen Planus Lesions in a Population From Iran. [PDF]

open access: yesClin Exp Dent Res
Jokar E   +6 more
europepmc   +1 more source

SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands. [PDF]

open access: yesProc Natl Acad Sci U S A
Hardwick JS   +12 more
europepmc   +1 more source

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