Results 221 to 230 of about 599,172 (303)

The mutual regulation of SOX12 and RNF168 modulates cisplatin resistance in esophageal squamous cell carcinoma cells by regulating DNA damage repair. [PDF]

Cell Biosci
Wang N, Yang L, Huang Y, Wang Y, Liu M, Yang J, Zeng Z, Xie G, Sun L, Han T, Yu B, Jin J.   +11 more
europepmc   +1 more source

Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications

Advanced Functional Materials, EarlyView.
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi, Norma Mallegni, Andrea Dorigato, Mario Milazzo   +3 more
wiley   +1 more source

Blockade of the KRAS-FOSL1 axis elicits DNA damage repair deficiency exploitable with local and systemic genotoxic therapies

Vicent S, Welch C, Novoa-Jaso G, Vasquez-Valencia C, Macaya I, Jimenez-Alonso JJ, Subrizio A, Fernández-Lagos A, Llorente S, Jimenez M, Prados-Carvajal R, Moreno H, Lopez I, Bakartxo N, Rub J, Ratia ACD, Battuello P, Bujanda-Cundin X, Huertas P, Macaruya T, Paz-Ares L, Crisafulli G, Calvo A, Guruceaga E, Tammela T, Martinez-Monge R, Lecanda F, Bardelli A, Ferrer I, Tian T, Russo M.   +30 more
europepmc   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Pathogenic variation in human DNA damage repair genes was originated from the evolutionary process of modern humans. [PDF]

Genes Dis
Li J, Zhao B, Qin Z, Kou SH, Chian JS, Xiao F, Lei H, Andaluz S, He J, Sinha S, Mao X, Wang SM.   +11 more
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

BRD9-p53-E2F1 circuit orchestrates cell growth and DNA damage repair in gastric cancer. [PDF]

Mol Cancer
Zhou Q, Wang Q, Duan Y, Zhang C, Liu T, Liu H, Zhao M, Hu Z.   +7 more
europepmc   +1 more source

Understanding DNA damage repair

Materials Today, 2012
openaire   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Impact of DNA damage repair alterations on real-world response to therapy in metastatic colorectal cancer. [PDF]

ESMO Open
Miotke L, Norton C, Rubnitz Z, Florou V, Nevala-Plagemann C, Garrido-Laguna I.   +5 more
europepmc   +1 more source