Results 231 to 240 of about 2,368,060 (250)
Base editing of organellar DNA with programmable deaminases
Nature Reviews Molecular Cell Biology, 2023 Mitochondria and chloroplasts are organelles that include their own genomes, which encode key genes for ATP production and carbon dioxide fixation, respectively.
Jia Chen, Jin-Soo Kim
exaly +2 more sources
CRISPR-Cas9 DNA Base-Editing and Prime-Editing
International Journal of Molecular Sciences, 2020 Many genetic diseases and undesirable traits are due to base-pair alterations in genomic DNA. Base-editing, the newest evolution of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas-based technologies, can directly install point ...
Michelle E McClements +2 more
exaly +2 more sources
Editing DNA Methylation in Mammalian Embryos
International Journal of Molecular Sciences, 2020 DNA methylation in mammals is essential for numerous biological functions, such as ensuring chromosomal stability, genomic imprinting, and X-chromosome inactivation through transcriptional regulation.
Kazuo Yamagata +2 more
exaly +2 more sources
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Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases
Cell, 2022Kayeong Lim, Seonghyun Lee, Jin-Soo Kim
exaly
Functional interrogation of DNA damage response variants with base editing screens
Cell, 2021Angelo Taglialatela, Raúl Rabadán
exaly
A DNA Origami-Based Gene Editing System for Efficient Gene Therapy in Vivo
Angewandte Chemie - International Edition, 2023Jianbing Liu, Baoquan Ding, Yuang Wang
exaly
DNA-free gene editing in plants: a brief overview
Biotechnology and Biotechnological Equipment, 2021Ivelin Pantchev
exaly