Results 101 to 110 of about 4,748,303 (367)

Molecular Dynamics Simulations of a Nucleosome and Free DNA [PDF]

open access: yesarXiv, 2004
Nucleosomes organize the folding of DNA into chromatin and significantly influence transcription, replication, regulation and repair. All atom molecular dynamics simulations of a nucleosome and of its 146 basepairs of DNA free in solution have been conducted.
arxiv  

DNA extraction for streamlined metagenomics of diverse environmental samples.

open access: yesBioTechniques, 2017
A major bottleneck for metagenomic sequencing is rapid and efficient DNA extraction. Here, we compare the extraction efficiencies of three magnetic bead-based platforms (KingFisher, epMotion, and Tecan) to a standardized column-based extraction platform ...
C. Marotz   +5 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Effectiveness of a novel extraction method for semen: comparison using liquid samples and dried stains [PDF]

open access: yes, 2016
Forensic analysis of deoxyribonucleic acid (DNA) collected from sexual assault evidence is a multi-step process that requires a great amount of time and resources.
Cassis, Patricia Rose
core   +1 more source

The Impact of Submersion on the Quantification of Host and Bacterial DNA [PDF]

open access: yes, 2020
The Impact of Submersion on the Quantification of Host and Bacterial DNA Grace Sprouse, Depts. of Forensic Science and Chemistry, with Dr. Catherine Connon, Dept. of Forensic Science and Dr. Baneshwar Singh, Dept.
Sprouse, Grace
core   +1 more source

Nucleic acid extraction from formalin-fixed paraffin-embedded cancer cell line samples: a trade off between quantity and quality? [PDF]

open access: yes, 2016
Background: Advanced genomic techniques such as Next-Generation-Sequencing (NGS) and gene expression profiling, including NanoString, are vital for the development of personalised medicines, as they enable molecular disease classification.
A Kalmar   +31 more
core   +1 more source

New Measurements of DNA Twist Elasticity [PDF]

open access: yes, 1997
The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this new material parameter. We extract its value from a recent experiment.
arxiv   +1 more source

A simplified DNA extraction protocol for unsorted bulk arthropod samples that maintains exoskeletal integrity

open access: yesEnvironmental DNA, 2019
High-throughput DNA sequencing offers an efficient tool for assessing the taxonomic content of bulk arthropod samples. Many current DNA extraction protocols however require extensive handling of samples, like specimen-based DNA extractions, or sorting of
M. Nielsen   +3 more
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Ekstraksi Dna Collocalia Fuchiphaga Dengan Metode Phenol Chloroform Extraction Dari Berbagai Material Sumber Genetik [PDF]

open access: yes, 2013
DNA extraction is the first important step in molecular study. The aim of this research was to compare DNA extraction protocols, PCE and extraction kit for each genetic material sources (blood and feathers).
Hendra, H. (Hendra)   +3 more
core  

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