Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A simple and rapid DNA extraction method from leaves of grapevine suitable for polymerase chain reaction analysis. [PDF]
The genomic grapevine (Vitis vinifera L.) DNA extraction is difficult because of secondary metabolites that interfere with DNA isolation procedures and subsequent applications.
ALFONZO, Antonio +5 more
core +1 more source
A list of all protocols used, from Zymo Research with slight modification. Additionally, protocols for measurement of purity and concentration are listed as well. D6010 is used when there are only a handful of samples and we use tubes, with the corresponding clean and concentrate protocol being D4013 .
openaire +1 more source
Quality of DNA Extracted from Mouthwashes [PDF]
A cost effective, safe and efficient method of obtaining DNA samples is essential in large scale genetic analyses. Buccal cells are an attractive source of DNA, as their collection is non-invasive and can be carried out by mail. However, little attention has been given to the quality of DNA extracted from mouthwashes.Mouthwash-derived DNA was extracted
Zayats, T +5 more
openaire +6 more sources
Evaluation of Oral Cavity DNA Extraction Methods on Bacterial and Fungal Microbiota
The objective of this study was to evaluate the most effective method of DNA extraction of oral mouthwash samples for use in microbiome studies that utilize next generation sequencing (NGS).
J. Rosenbaum +8 more
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Whole Genome Sequencing of A Healthy Sundanese Individual As an Initial Study for Sundanese Population Genetic Reference Foundation [PDF]
Sundanese is the second-largest tribe in Indonesia. Despite its substantial and diverse population, the application and database of whole-genome sequencing in Indonesia, especially among Sundanese individuals, are limited.
Jamilah Richa Wijayanti +4 more
doaj +1 more source
Investigation of Bm86 gene analog sequence in some Iranian populations of Hyalomma anatolicum species [PDF]
Ticks are an important problem among zoonotic diseases. Main veterinary species of hard ticks are: Hyalomma sp. Boophilus sp and Rhipicephalus sp. Among them Hyalomma sp. have widespread distribution in Iran and Middle East.
S. Abdollahi +2 more
doaj +1 more source
Satellite DNA as a target for TaqMan real-time PCR detection of the pinewood nematode, Bursaphelenchus xylophilus [PDF]
The pinewood nematode (PWN), Bursaphelenchus xylophilus , is a major pathogen of conifers, which impacts on forest health, natural ecosystem stability and international trade. As a consequence, it has been listed as a quarantine organism in Europe.
BOONHAM, NEIL +9 more
core +1 more source

