Results 191 to 200 of about 33,266 (249)

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Development and application of genome-derived SSR markers for genetic diversity analysis, molecular fingerprinting, and core collection construction in bougainvillea (Bougainvillea spp.). [PDF]

BMC Genomics
Gan R, Han Y, Rao D, Li T, Wu E, Cui Y, Chen Y.   +6 more
europepmc   +1 more source

Genes, fish and fisheries: translating science into policy

Journal of Fish Biology, EarlyView.
Abstract The 2024 Annual Symposium of the Fisheries Society of the British Isles reviewed the burgeoning impact of ‘omics’ technologies on fish ecology, management and forecasting. As with life sciences more generally, major advances in speed, cost‐effectiveness and breadth of applications in ‘omics’ has had profound societal and environmental impacts.
Gary R. Carvalho
wiley   +1 more source

Single-molecule electrical protein fingerprinting in solid-state nanopores. [PDF]

Clin Transl Med
Soni N, Meller A.
europepmc   +1 more source

Chronic thermal stress affects growth, liver morphology and molecular responses but allows recovery at optimal temperature in juvenile zebrafish (Danio rerio)

Journal of Fish Biology, EarlyView.
Abstract Climate‐driven aquatic heatwaves pose an increasing threat to fish populations by inducing prolonged thermal stress. However, the resilience of teleosts to chronic heat exposure and their capacity for recovery remains poorly understood. This study investigated the effects of chronic high‐temperature exposure on juvenile zebrafish (Danio rerio).
Monique Adzijovski, Aaron G. Schultz, Jemma Bergfeld, Luis O. B. Afonso   +3 more
wiley   +1 more source

Optimized Cas‐SF01 gene‐editing toolbox shortens flowering timing in commercial maize inbred JING724

Journal of Integrative Plant Biology, EarlyView.
The gene‐editing tool Cas‐SF01 was optimized to maximize its efficiency in maize. The Cas‐SF01‐TREX2 configuration was superior in enabling high‐purity gene mutations. This toolkit enabled commercial maize to flower seven days earlier without yield loss, thereby securing harvests and accelerating crop breeding.
Mengyuan Liu, Yao Wang, Lu Zhang, Xiang Zhang, Xiaqing Wang, Xinxiang Liu, Yue Fu, Xiaoxu Li, Ziheng Song, Ya Liu, Ronghuan Wang, Jiuran Zhao   +11 more
wiley   +1 more source

Whole-genome sequencing reveals genomic diversity and population structure of mango germplasm from the Jazan region of Saudi Arabia. [PDF]

Front Plant Sci
Almarri NB, Mostafa SM, Alsofuani NM, Osman S, Alomran SM, A Ibrahim M, Alrashidi I, Al-Haidar OA, Ahmad S.   +8 more
europepmc   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

AI and Epigenetics: A New Opportunity for Early Pancreatic Cancer Detection in Australia

ANZ Journal of Surgery, EarlyView.
Jaswinder S. Samra, Krishna Kotecha, Anubhav Mittal   +2 more
wiley   +1 more source

The ciliary neurotrophic factor induces Stat3 phosphorylation in distinctive cytotypes of organs involved in body metabolism: An immunohistochemical study

Journal of Anatomy, EarlyView.
p‐STAT3‐positive cells in metabolically relevant peripheral organs and tissues from mice administered with recombinant CNTF (0.3 mg/kg). Abstract Administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight in both humans and experimental animals, where it also ameliorates hyperglycemia, hyperinsulinemia, and dyslipidemia ...
Chiara Galli, Georgia Colleluori, Jessica Perugini, Edoardo Scopini, Ilenia Severi, Gaia Grandin, Antonio Giordano   +6 more
wiley   +1 more source