Results 201 to 210 of about 1,519,960 (260)

Bridging preclinical development and clinical manufacturing: a translational GMP-Platform for lentiviral vector production in academic CAR T-Cell therapy. [PDF]

J Transl Med
Lara-Chica M, Arribas-Arribas B, Muñoz-García R, Dolores de la Rosa-Garrido M, Montiel-Aguilera MA, Bermejo-González M, Márquez-Pérez E, Hernández-Díaz P, Guijarro-Albaladejo B, Sierro-Martínez B, Pérez-Simón JA, Carmona-Sánchez G, García-Guerrero E.   +12 more
europepmc   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

Assessing the contribution of rare DNA states to cancer mutational signatures using sequence-specific conformational fingerprinting. [PDF]

Nat Commun
Szekely O, Lee Y, Rangadurai AK, Guseva S, Cooksey J, Faison EM, Zalenski N, Zhang Q, Suo Z, Al-Hashimi HM.   +9 more
europepmc   +1 more source

Children Born Using Ejaculated Sperm From Men With Klinefelter Syndrome. Is Sperm Production Associated With Testicular Volume?

Andrology, EarlyView.
ABSTRACT Background A large number of children have been born using testicular sperm from men with Klinefelter syndrome (KS), whereas reports of children conceived using ejaculated sperm are rare. Objective To review all published cases of children conceived using ejaculated sperm from men with KS, assess their health and karyotype, and evaluate ...
Jens Fedder, Freja Sørensen
wiley   +1 more source

Genome-wide association mapping of distinctness, uniformity and stability traits and varietal identification in rice (Oryza sativa L.). [PDF]

J Sci Food Agric
Kalakunta Sri S, Mangala RS, Shaik NU, Gannavarapu Katyayani SV, Ganesan A, Kalluru S, Ramireddy E, Vemireddy LR.   +7 more
europepmc   +1 more source

Development of KASP molecular markers and fingerprinting based on reduced representation genome sequencing of garlic. [PDF]

Front Plant Sci
Yang Q, Fan J, Song X, Zhang B, Zhao Y, Lu X, Ge J, Liu C, Li M, Liu G, Feng Y, Yang F.   +11 more
europepmc   +1 more source

From Model to Practice: Testing Near‐Infrared Spectroscopy as a Bone Collagen Prescreening Tool

Archaeometry, EarlyView.
ABSTRACT Collagen is a vital archaeological material, preserving biochemical signatures that provide insights into past environments, diets, and human–animal interactions. However, diagenetic processes can lead to rapid and often inconspicuous degradation of collagen. Given the variability in collagen preservation and its significance for analyses such
Christina Ryder, Gerardo Celis, Thibaut Devièse, Thomas Higham, Katerina Douka, Loren Davis, Matthew Collins, Angela Perri, Heather Thakar, Matt Sponheimer   +9 more
wiley   +1 more source

A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8

Brain Pathology, EarlyView.
We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren, Carola Hedberg‐Oldfors, Kittichate Visuttijai, Sara Nordström, Hans Goebel, Anders Oldfors   +5 more
wiley   +1 more source

Exosome-Based Liquid Biopsy in Biliary Tract Cancer: Nanotechnology-Enabled Strategies and Future Perspectives. [PDF]

Int J Nanomedicine
Choi Y, Yang J, Kim J, Enkhtaivan K, Son J, Jang J, Lee HY, Choi J.   +7 more
europepmc   +1 more source