Results 201 to 210 of about 204,474 (261)

Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study. [PDF]

Hum Reprod
Humaidan P, Povlsen BB, Drakeley AJ, Jensen MB, Gabrielsen AV, McDowell SH, Moore L, Ledgerwood CJ, Rae L, Sloan A, Lawlor M, Poots L, Bailie E, Lunt RL, Newton E, Gregoire RC, Moore TCB, Esteves SC.   +17 more
europepmc   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Effect of sperm DNA fragmentation on embryo euploidy rate in assisted reproductive technologies: a systematic review and meta-analysis. [PDF]

Eur J Med Res
Wan B, Fu Y, Ma N, Zhou Z, Lu W.
europepmc   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Sperm DNA Fragmentation in Men with Varicocele: A Systematic Review and Meta-Analysis. [PDF]

World J Mens Health
Palani A, Çayan S, Cannarella R, Saleh R, Altay B, Kadihasanoglu M, Harraz A, Dimitriadis F, Ceyhan E, Rezano A, Zwamel AH, Ibrahim W, Benabbou A, Margiana R, Gnoneye E, Rabin MMM, Omirinde J, Esmaeili V, Zini A, Arafa M, Elbardisi H, Toprak T, Dursun M, Khalafalla K, Salvio G, Chung E, Crafa A, Shah R, Agarwal A.   +28 more
europepmc   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Author Correction: RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells. [PDF]

Commun Biol
Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.   +20 more
europepmc   +1 more source

Viable sperm DNA fragmentation index (SDF) provides better diagnostic accuracy than total SDF in male infertility: a cross-sectional study. [PDF]

Transl Androl Urol
Deng T, Yu W, Yao J, Li X, Fu Z, Xie Y, Pu J, Chen K, Yao B, Lin X, Wang W.   +10 more
europepmc   +1 more source

Impact of ejaculation frequency on semen parameters and DNA fragmentation: a cross-sectional study. [PDF]

Reprod Biol Endocrinol
Xi Q, Kong Q, Lv X, Dai R, Yu Y.
europepmc   +1 more source

The Relationship Between Sperm Midpiece Details and DNA Fragmentation in Human Sperm. [PDF]

Reprod Sci
Ibis MA, Mencik NO, Öztürk B, Karaburun MC, Akpinar C, Akıncı A, Haberal HB, Aydos K, Yaman O.   +8 more
europepmc   +1 more source