Results 101 to 110 of about 12,279 (184)

Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]

, 2016
Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R, Guidotti, Alessandro, MATRISCIANO, FRANCESCO, NICOLETTI, Ferdinando, PANACCIONE, ISABELLA   +4 more
core   +2 more sources

Predators of the two paropsine leaf beetles Paropsisterna cloelia and Paropsis charybdis in eucalypt plantations in Marlborough, New Zealand Prädatoren der zwei Blattkäfer Paropsisterna cloelia and Paropsis charybdis in Eukalyptusplantagen in Marlborough, Neuseeland

Agricultural and Forest Entomology, Volume 28, Issue 2, Page 137-148, May 2026.
Coccinellidae (Coleoptera), Miridae (Hemiptera), Hemerobiidae (Neuroptera), Pentatomidae (Hemiptera), Anystidae (Acari), Erythraeidae (Acari) and spiders (Araneidae, Oxyopidae and Salticidae) fed on the invasive paropsine leaf beetles in Marlborough, New Zealand.
Carolin Weser, Manpreet K. Dhami, Elena Moltchanova, Ana Podolyan, Toni M. Withers, Stephen M. Pawson   +5 more
wiley   +1 more source

DNA damage measurements within tissue samples with Repair Assisted Damage Detection (RADD)

Current Research in Biotechnology, 2019
Exposures to genotoxic carcinogens and reactive species result in strand breaks and a spectrum of covalent modifications to DNA that can induce mutations and contribute to the initiation and progression of cancer. Measurements of DNA damage within tissue
Kevin J. Lee, Elise Mann, Luciana Madeira da Silva, Jennifer Scalici, Natalie R. Gassman   +4 more
doaj   +1 more source

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones [PDF]

, 2016
Our previous paper (Wilkinson et al, 2016) used high-resolution cryo-electron microscopy to solve the structure of the Escherichia coli RecBCD complex, which acts in both the repair of double-stranded DNA breaks and the degradation of bacteriophage DNA ...
Aedo, Afonine, Amundsen, Amundsen, Bannister, Baños-Sanz, Cano, Cirz, CLSI, Cole, Court, Court, Cronan, Darrigo, Datta, Dillingham, Emsley, Forage, González-Soltero, Henderson, Kennaway, Kulkarni, Li, Liu, Liu, López, McDaniel, Murphy, Murphy, Murphy, Muyrers, Paczosa, Pettersen, Robinson, Sakaki, Scheres, Singleton, Tamae, Urnavicius, Wang, Wiegand, Wigley, Wilkinson, Zhang, Zhang   +44 more
core   +5 more sources

The PagDMG6341–PagWD40–PagPOLD4 Module Coordinates Base Excision Repair in ‘84K’ Poplar (Populus alba × P. glandulosa)

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2956-2969, May 2026.
ABSTRACT Base excision repair (BER) is a critical pathway for repairing damaged DNA bases in cells; however, the mechanisms of protein recruitment and interaction in this pathway remain largely unexplored in higher plants. In this study, we used ‘84K’ poplar (Populus alba × P.
Aoyu Ling, Yijia Jin, Yufei Xia, Shenxiu Jiang, Jianghai Shu, Xiaotong Hu, Kang Du, Pingdong Zhang, Xiangyang Kang   +8 more
wiley   +1 more source

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou, Wan Fu, Shizuo Liu, Zili Zhang, Hanyan Luo, Qing Zhong   +5 more
wiley   +1 more source

DNA repair and disease: insights from the human DNA glycosylase NEIL family

Experimental and Molecular Medicine
The base excision repair pathway protects DNA from base damage via oxidation, deamination, alkylation and methylation. DNA glycosylases are key enzymes that recognize damaged bases in a lesion-specific manner and initiate the base excision repair process.
Yuna Hwang, Su-Jin Kang, Jieun Kang, Jeongwoo Choi, Seung-Jin Kim, Sunbok Jang   +5 more
doaj   +1 more source

Surveying the repair of ancient DNA from bones via high-throughput sequencing

BioTechniques, 2015
DNA damage in the form of abasic sites, chemically altered nucleotides, and strand fragmentation is the foremost limitation in obtaining genetic information from many ancient samples. Upon cell death, DNA continues to endure various chemical attacks such
Nathalie Mouttham, Jennifer Klunk, Melanie Kuch, Ron Fourney, Hendrik Poinar   +4 more
doaj   +1 more source

War without weapons:constitution of healthy and pathological phenotypes associated with polymorphisms in genes involved in the maintenance of genome integrity [PDF]

, 2012
Capacity to repair DNA damage may vary significantly between individuals coming out as healthy on routine physical and laboratory examinations. This variance does not generally cause distress or disease unless in case that specific triggers are present ...
Khalil, Hilal S., Oluwaseun, Omoboye Adebola   +1 more
core   +3 more sources

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, Volume 13, Issue 20, 9 April 2026.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source