Results 151 to 160 of about 20,880 (290)
The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status. [PDF]
, 2017 DNA methylation is associated with gene silencing in eukaryotic organisms. Although pathways controlling the establishment, maintenance and removal of DNA methylation are known, relatively little is understood about how DNA methylation influences gene ...
Chen, Xuemei +20 more
core +3 more sources
Escherichia coli K-12 mutants deficient in uracil-DNA glycosylase [PDF]
, 1978 Bruce K. Duncan +2 more
openalex +1 more source
The FEBS Journal, EarlyView.Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres +10 more
wiley +1 more source
Reading and Misreading 8-oxoguanine, a Paradigmatic Ambiguous Nucleobase
Crystals, 2019 7,8-Dihydro-8-oxoguanine (oxoG) is the most abundant oxidative DNA lesion with dual coding properties. It forms both Watson−Crick (anti)oxoG:(anti)C and Hoogsteen (syn)oxoG:(anti)A base pairs without a significant distortion of a B-DNA helix.
Anna V. Yudkina +4 more
doaj +1 more source
Uracil DNA-glycosylase from HeLa cells: general properties, substrate specificity and effect of uracil analogs [PDF]
, 1981 Hans E. Krokan, Christian Urs Wittwer
openalex +1 more source
Transcription‐coupled repair: tangled up in convoluted repair
The FEBS Journal, EarlyView.In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher +3 more
wiley +1 more source
DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase [PDF]
arXiv, 2014 Escherichia coli DNA polymerase V (pol V), a heterotrimeric complex composed of UmuD'2C, is marginally active. ATP and RecA play essential roles in the activation of pol V for DNA synthesis including translesion synthesis (TLS). We have established three features of the roles of ATP and RecA.
arxiv
Divergent structures of Mammalian and gammaherpesvirus uracil DNA glycosylases confer distinct DNA binding and substrate activity. [PDF]
DNA Repair (Amst), 2023 Mu Y +6 more
europepmc +1 more source
Base excision repair and the role of MUTYH [PDF]
, 2007 The correction of exogenous and endogenous environmental insult to DNA involves a series of DNA repair mechanisms that reduce the likelihood of mutation accumulation and hence an increased probability of tumour development.
Kairupan, Carla, Scott, Rodney J
core +3 more sources
Medical and Veterinary Entomology, EarlyView.We identified Culex pipiens bloodmeals at the species level in natural, agricultural and peri‐urban habitats and calculated host preferences based on forage ratios. This analysis showed Passeriformes, and in particular Columba livia, Passer montanus and Turdus sp., to be the preferred Cx. pipiens hosts.
Víctor Rodríguez‐Valencia +9 more
wiley +1 more source