Results 71 to 80 of about 38,912 (254)
Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments
Water and Environment Journal, EarlyView.Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze +3 more
wiley +1 more source
Segmentally Variable Genes: A New Perspective on Adaptation [PDF]
, 2004 Genomic sequence variation is the hallmark of life and is key to understanding diversity and adaptation among the numerous microorganisms on earth. Analysis of the sequenced microbial genomes suggests that genes are evolving at many different rates.
Kasif, Simon +2 more
core +4 more sources
Food Science &Nutrition, Volume 14, Issue 2, February 2026.Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza +7 more
wiley +1 more source
DNA gyrase could be a crucial regulatory factor for growth and survival of Mycobacterium leprae
Scientific Reports, 2019 Leprosy, an important infectious disease in humans caused by Mycobacterium leprae (Mle), remains endemic in many countries. Notably, the pathogen cannot be cultured in vitro, except in mouse footpads in vivo.
Hyun Kim +7 more
doaj +1 more source
The latch modulates nucleotide and DNA binding to the helicase-like domain of Thermotoga maritima reverse gyrase and is required for positive DNA supercoiling [PDF]
, 2017 Reverse gyrase is the only topoisomerase that can introduce positive supercoils into DNA in an ATP-dependent process. It has a modular structure and harnesses a helicase-like domain to support a topoisomerase activity, thereby creating the unique ...
del Toro Duany, Yoandris +3 more
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Extensive structure‐activity relationship study of albicidin’s C‐terminal dipeptidic p‐aminobenzoic acid moiety [PDF]
, 2019 Albicidin is a recently described natural product that strongly inhibits bacterial DNA gyrase. The pronounced activity, particularly against Gram‐negative bacteria, turns it into a promising lead structure for an antibacterial drug.
Behroz, Iraj +7 more
core +1 more source
Mechanism of Inhibition of DNA Gyrase by ES‐1273, a Novel DNA Gyrase Inhibitor [PDF]
Microbiology and Immunology, 2007 AbstractWe investigated the mode of action of ES‐1273, a novel DNA gyrase inhibitor obtained by optimization of ES‐0615, which was found by screening our chemical library using anucleate cell blue assay. ES‐1273 exhibited the same antibacterial activity against S. aureus strains with amino acid change(s) conferring quinolone‐ and coumarin‐resistance as
Yoshihiro, Oyamada +5 more
openaire +2 more sources
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim +6 more
wiley +1 more source
mSphere, 2020 Although DNA-compacting proteins have been extensively characterized in vitro, knowledge of their DNA binding dynamics in vivo is greatly lacking.
Sonja Schibany +3 more
doaj +1 more source
Guiding strand passage: DNA-induced movement of the gyrase C-terminal domains defines an early step in the supercoiling cycle [PDF]
, 2017 DNA gyrase catalyzes ATP-dependent negative supercoiling of DNA in a strand passage mechanism. A double-stranded segment of DNA, the T-segment, is passed through the gap in a transiently cleaved G-segment by coordinated closing and opening of three ...
Klostermeier, Dagmar, Lanz, Martin A.
core