Results 61 to 70 of about 349,528 (198)

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

Advanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li, Andi Dian Permana, Juan Domínguez‐Robles, Muh Nur Amir, Habibie Habibie, Qonita Kurnia Anjani, Li Zhao, Natalia Moreno‐Castellanos, Ryan F Donnelly, Eneko Larrañeta   +9 more
wiley   +1 more source

5-Methyl-cytosine stabilizes DNA but hinders DNA hybridization revealed by magnetic tweezers and simulations. [PDF]

Nucleic Acids Res, 2022
Zhao XC, Dong HL, Li XL, Yang HY, Chen XF, Dai L, Wu WQ, Tan ZJ, Zhang XH.   +8 more
europepmc   +1 more source

Hybridization methods for DNA sequencing

Genomics, 1991
I have conducted a general analysis of the practicability of using oligonucleotide hybridization to sequence DNA. Any DNA sequence may be sequenced by hybridization with a complete panel of oligonucleotides. However, sequencing DNA segments over 2 kb long requires an unrealistic number of hybridization reactions.
openaire   +3 more sources

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Fabrication of Silicon Nanowire Sensors for Highly Sensitive pH and DNA Hybridization Detection. [PDF]

Nanomaterials (Basel), 2022
Abd Rahman SF, Yusof NA, Md Arshad MK, Hashim U, Md Nor MN, Hamidon MN.   +5 more
europepmc   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source

The stability and number of nucleating interactions determine DNA hybridization rates in the absence of secondary structure. [PDF]

Nucleic Acids Res, 2022
Hertel S, Spinney RE, Xu SY, Ouldridge TE, Morris RG, Lee LK.   +5 more
europepmc   +1 more source

Genomic DNA Labeling for Hybridization with DNA Arrays [PDF]

BioTechniques, 2003
Igor Ivanov, Peter Amon
openaire   +4 more sources

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

Advanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer, Adriana Vilaça, Miguel Xavier, Rafael Santos, Ariel Ionescu, María Lázaro, Victoria Leiro, Eran Perlson, Sofia C. Guimarães, Ben M. Maoz, Ana P. Pêgo   +10 more
wiley   +1 more source

Microchemomechanical devices using DNA hybridization. [PDF]

Proc Natl Acad Sci U S A, 2021
Zhu G, Hannel M, Sha R, Zhou F, Ben Zion MY, Zhang Y, Bishop K, Grier D, Seeman N, Chaikin P.   +9 more
europepmc   +1 more source