Results 71 to 80 of about 2,573,553 (254)

Safeguarding integrity: a guide to the integrity system in Victoria [PDF]

, 2014
The Safeguarding Integrity Guide aims to help public sector employees and the broader community understand Victoria\u27s integrity system and its key agencies.

core  

DNA integrity gels.

, 2016
(A) Illustrative DNA Integrity gels with gel scores. Example integrity gels for (B) Holstein Friesian cattle and (C) Soay sheep. Individual samples (represented by numbers in image) that were extracted with different DNA extraction protocols. (PG: Gentra
Joanna J. Ilska (3207378), Rebecca Holland (3207384), Bruce Whitelaw (3207393), Georgios Banos (357423), Androniki Psifidi (357421), Sarah Underwood (3207396), Daniel H. Nussey (326661), Jennifer Fairlie (3207381), Luise A. Seeker (3207390), Ainsley Bagnall (420739), Mike Coffey (3207387)   +10 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

DNA damage responses to loss of telomere integrity [PDF]

, 2013
Linear genomes end in characteristic structures consisting of repetitive DNA and proteins: the telomeres. These play two critical roles: on one hand they avoid the of loss of genetic information due to the incomplete replication of the chromosome ends ...
Carlos, Ana Rita
core   +1 more source

Dietary vitamin C supplementation improves semen quality and antioxidant activity in Japanese quail under summer heat stress

Ovozoa: Journal of Animal Reproduction
Heat stress severely affects the redox balance of poultry semen, as the limited supply of natural antioxidants is unable to neutralize the excessive production of free radicals. This oxidative stress can reduce sperm quality and reproductive productivity
Aimen Jahangir, Shamim Akhter, Sumiyyah Zuha, Bushra Allah Rakha, Hajrah Raad Tihami, Hafsah Tihami   +5 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Pathological replication in cells lacking RecG DNA translocase [PDF]

, 2009
This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors.Little is known about what happens when forks meet to complete DNA replication in any organism.
Lloyd, RG, Robert G. Lloyd, Lynda Harris, Harris, L, Christian J. Rudolph, Amy L. Upton, Rudolph, CJ, Upton, AL   +7 more
core   +1 more source

Pleural fluid cell-free DNA integrity index to identify cytologically negative malignant pleural effusions including mesotheliomas

BMC Cancer, 2012
Background The diagnosis of malignant pleural effusions (MPE) is often clinically challenging, especially if the cytology is negative for malignancy. DNA integrity index has been reported to be a marker of malignancy.
Sriram Krishna B, Relan Vandana, Clarke Belinda E, Duhig Edwina E, Windsor Morgan N, Matar Kevin S, Naidoo Rishendran, Passmore Linda, McCaul Elizabeth, Courtney Deborah, Yang Ian A, Bowman Rayleen V, Fong Kwun M   +12 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Evaluation of Serum Dna Integrity as a Screening and Prognostic Tool in Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma

The International Journal of Biological Markers, 2010
Background Hepatocellular carcinoma (HCC) is a common malignancy in Egypt due to the high frequency of hepatitis C virus (HCV) infection among the general population. Circulating free DNA is a potential molecular marker for the diagnosis and prognosis of
Sherien F. El-Shazly MD, Manal A. Eid, Hesham A. El-Sourogy, Gehan F. Attia, Sherif A. Ezzat   +4 more
doaj   +1 more source