Results 1 to 10 of about 226,052 (289)

Ligase-Catalyzed Transcription and Reverse Transcription of XNA by T3 DNA Ligase. [PDF]

Curr Protoc
Khamissi N, Rustico L, Hili R.
europepmc   +3 more sources

Ataxia-telangiectasia mutated kinase inhibition overcomes gemcitabine resistance in intrahepatic cholangiocarcinoma via DNA ligase I-dependent repair vulnerability. [PDF]

Cancer Gene Ther
Lin SH, Pan YR, Hung TH, Huang WK, Yeh CN.   +4 more
europepmc   +3 more sources

Berberine Sensitises Breast Cancer Cells to Radiation via the Attenuation of DNA Ligase III. [PDF]

J Cell Mol Med
Sun Y, Li C, Yin H, Li K, Wang Y, Zhang S, Zhao Y, Wang J, Mao W.   +8 more
europepmc   +3 more sources

The discovery of the mechanisms of biological synthesis of nucleic acids: 1959 Nobel laureates S. Ochoa and A. Kornberg [PDF]

The Ukrainian Biochemical Journal, 2021
Alongside the chemical and physical research of nucleic acids in the 1940s-50s, the mechanisms of their biosynthesis were investigated. Thus, in 1959, Severo Ochoa and Arthur Kornberg were awarded the Nobel Prize in Physiology or Medicine for the ...
O. P. Matyshevska, V. M. Danilova, S. V. Komisarenko   +2 more
doaj   +1 more source

Crystal structure of ATP-dependent DNA ligase from Rhizobium phage vB_RleM_P10VF. [PDF]

Acta Crystallogr F Struct Biol Commun
Rothweiler U, Leiros HKS, Williamson A.
europepmc   +3 more sources

Influence of the ATP-dependent DNA ligase, Lig E, on <i>Neisseria gonorrhoeae</i> microcolony and biofilm formation. [PDF]

Biofilm
Pan J, Albarrak A, Hicks J, Williams D, Williamson A.   +4 more
europepmc   +2 more sources

Molecular basis for RNA discrimination by human DNA ligase 1. [PDF]

Nucleic Acids Res
Tumbale PP, Jurkiw TJ, Krahn JM, Bokil NV, Admiraal SJ, Pedersen LC, Williams JS, Kunkel TA, O'Brien PJ, Williams RS.   +9 more
europepmc   +3 more sources

Comparative analysis of the end-joining activity of several DNA ligases. [PDF]

PLoS ONE, 2017
DNA ligases catalyze the repair of phosphate backbone breaks in DNA, acting with highest activity on breaks in one strand of duplex DNA. Some DNA ligases have also been observed to ligate two DNA fragments with short complementary overhangs or blunt ...
Robert J Bauer, Alexander Zhelkovsky, Katharina Bilotti, Laura E Crowell, Thomas C Evans, Larry A McReynolds, Gregory J S Lohman   +6 more
doaj   +1 more source

Synthesis of novel pyridazine and pyrimidine linked pyrazole derivatives as DNA ligase 1 and IV inhibitors that induce apoptosis. [PDF]

Chem Biol Interact
Aishwarya S, Torres GC, Lopez-Saenz JA, Gutierrez DA, Kumar S, Madarakhandi A, Metikurki B, Teraiya N, Aguilera RJ, Karki SS.   +9 more
europepmc   +3 more sources

Escherichia coli DNA ligase B may mitigate damage from oxidative stress. [PDF]

PLoS ONE, 2017
Escherichia coli encodes two DNA ligases, ligase A, which is essential under normal laboratory growth conditions, and ligase B, which is not. Here we report potential functions of ligase B.
Truston J Bodine, Michael A Evangelista, Huan Ting Chang, Christopher A Ayoub, Buck S Samuel, Richard Sucgang, Lynn Zechiedrich   +6 more
doaj   +1 more source