Results 1 to 10 of about 145,020 (273)

Transcriptome-wide analysis reveals core transcriptional regulators associated with culm development and variation in Dendrocalamus sinicus, the strongest woody bamboo in the world

open access: yesHeliyon, 2022
Transcription factors (TFs) play indispensable roles in plant development and stress responses. As the largest woody bamboo species in the world, Dendrocalamus sinicus is endemic to Yunnan Province, China, and possesses two natural variants characterized
Lingna Chen   +4 more
doaj   +1 more source

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]

open access: yes, 2013
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund   +92 more
core   +1 more source

Design and Synthesis of Ag Nanocluster Molecular Beacon for Adenosine Triphosphate Detection

open access: yesJournal of Analytical Methods in Chemistry, 2019
This study presents a fluorescence method for detecting adenosine triphosphate (ATP) based on a label-free Ag nanocluster molecular beacon (MB) with high sensitivity.
Xiaoshuang Li   +7 more
doaj   +1 more source

The eukaryotic Pso2/Snm1/Artemis proteins and their function as genomic and cellular caretakers

open access: yesBrazilian Journal of Medical and Biological Research, 2005
DNA double-strand breaks (DSBs) represent a major threat to the genomic stability of eukaryotic cells. DNA repair mechanisms such as non-homologous end joining (NHEJ) are responsible for the maintenance of eukaryotic genomes.
D. Bonatto   +3 more
doaj   +1 more source

The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling

open access: yesCell Discovery, 2022
Chromodomain helicase DNA binding protein (CHD) family plays critical roles in regulating gene transcription. The family is linked to cancer disease, but the family member’s role in tumorigenesis remains largely unknown.
Boyu Zhang   +14 more
doaj   +1 more source

Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates [PDF]

open access: yes, 2013
Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA
Bartlett, Edward   +2 more
core   +1 more source

Bioinformatics analysis of genes of Streptomyces xinghaiensis (fradiae) ATCC 19609 with a focus on mutations conferring resistance to oligomycin A and its derivatives

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objectives: The aim of this study was to obtain Streptomyces xinghaiensis (fradiae) ATCC 19609 mutants resistant to oligomycin A and its derivatives and to identify the underlying mechanism of resistance.
Aleksey A. Vatlin   +4 more
doaj   +1 more source

Growth arrest and DNA damage‐inducible alpha regulates muscle repair and fat infiltration through ATP synthase F1 subunit alpha

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Background Skeletal muscle fat infiltration is a common feature during ageing, obesity and several myopathies associated with muscular dysfunction and sarcopenia.
Wenjing You   +9 more
doaj   +1 more source

In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast

open access: yesCell Reports, 2019
Summary: Disassembly of the replisome is the final step of chromosome duplication in eukaryotes. In budding yeast and metazoa, cullin ubiquitin ligases are required to ubiquitylate the Cdc45-MCM-GINS (CMG) helicase that lies at the heart of the replisome,
Progya P. Mukherjee, Karim P.M. Labib
doaj   +1 more source

Spd2 assists Spd1 in modulation of RNR architecture but does not regulate deoxynucleotide pools [PDF]

open access: yes, 2014
In yeasts, small intrinsically disordered proteins (IDPs) modulate ribonucleotide reductase (RNR) activity to ensure an optimal supply of dNTPs for DNA synthesis. The S. pombe Spd1 protein can directly inhibit the large RNR subunit (R1), import the small
Basrai   +37 more
core   +1 more source

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