Results 21 to 30 of about 78,437 (236)
Characterization of a Thermophilic ATP-Dependent DNA Ligase from the Euryarchaeon Pyrococcus horikoshii [PDF]
Journal of Bacteriology, 2005 ABSTRACT Archaea encode a DNA ligase composed of a C-terminal catalytic domain typical of ATP-dependent ligases plus an N-terminal domain similar to that found in eukaryotic cellular and poxvirus DNA ligases. All archaeal DNA ligases characterized to date have ATP-dependent adenylyltransferase and nick-joining activities. However,
Niroshika, Keppetipola, Stewart, Shuman
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ATPase-dependent control of the Mms21 SUMO ligase during DNA repair.
PLoS Biology, 2015 Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA replication, the Mms21-branch of the SUMO pathway counteracts recombination intermediates at damaged replication forks, thus facilitating sister chromatid ...
Marcelino Bermúdez-López +11 more
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Molecules, 2017 The DNA ligases, enzymes that seal breaks in the backbones of DNA, are essential for all organisms, however bacterial ligases essential for DNA replication use β-nicotinamide adenine dinucleotide as their co-factor, whereas those that are essential in ...
Malgorzata Korycka-Machala +6 more
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Bioinformatic analysis of Tetrahymena thermophila ATP dependent DNA ligases
New Biotechnology, 2009 …
Akdamar, H. Acelya +2 more
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Design and Synthesis of Ag Nanocluster Molecular Beacon for Adenosine Triphosphate Detection
Journal of Analytical Methods in Chemistry, 2019 This study presents a fluorescence method for detecting adenosine triphosphate (ATP) based on a label-free Ag nanocluster molecular beacon (MB) with high sensitivity.
Xiaoshuang Li +7 more
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A Primer-dependent Polymerase Function of Pseudomonas aeruginosa ATP-dependent DNA Ligase (LigD) [PDF]
Journal of Biological Chemistry, 2005 Pseudomonas aeruginosa encodes two putative DNA ligases: a classical NAD(+)-dependent DNA ligase (LigA) plus an ATP-dependent DNA ligase (LigD). LigD exemplifies a family of bacterial proteins that consist of a ligase domain fused to flanking domains that resemble nucleases and/or polymerases. Here we purify LigD and show that it possesses an intrinsic
Hui, Zhu, Stewart, Shuman
openaire +2 more sources
The eukaryotic Pso2/Snm1/Artemis proteins and their function as genomic and cellular caretakers
Brazilian Journal of Medical and Biological Research, 2005 DNA double-strand breaks (DSBs) represent a major threat to the genomic stability of eukaryotic cells. DNA repair mechanisms such as non-homologous end joining (NHEJ) are responsible for the maintenance of eukaryotic genomes.
D. Bonatto +3 more
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Mutation-Driven Divergence and Convergence Indicate Adaptive Evolution of the Intracellular Human-Restricted Pathogen, Bartonella bacilliformis. [PDF]
PLoS Neglected Tropical Diseases, 2016 Among all species of Bartonella, human-restricted Bartonella bacilliformis is the most virulent but harbors one of the most reduced genomes. Carrión's disease, the infection caused by B.
Sandip Paul +2 more
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Heliyon, 2022 Transcription factors (TFs) play indispensable roles in plant development and stress responses. As the largest woody bamboo species in the world, Dendrocalamus sinicus is endemic to Yunnan Province, China, and possesses two natural variants characterized
Lingna Chen +4 more
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Cell Discovery, 2022 Chromodomain helicase DNA binding protein (CHD) family plays critical roles in regulating gene transcription. The family is linked to cancer disease, but the family member’s role in tumorigenesis remains largely unknown.
Boyu Zhang +14 more
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