A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation
BMC MicrobiologyBackground The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial genomes, including many disease-causing species.
Jolyn Pan +4 more
doaj +1 more source
Interplay between DNA Polymerases and DNA Ligases: Influence on Substrate Channeling and the Fidelity of DNA Ligation. [PDF]
J Mol Biol, 2019 Çağlayan M.
europepmc +1 more source
The yeast CDC9 gene encodes both a nuclear and a mitochondrial form of DNA ligase I [PDF]
, 1999 Martin Willer +3 more
openalex +1 more source
The E3 Ubiquitin Ligase TRIM21 Promotes HBV DNA Polymerase Degradation [PDF]
, 2020 Ting Mu +4 more
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Advanced Science, EarlyView.We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard +8 more
wiley +1 more source
DNA binding with a minimal scaffold: structure-function analysis of Lig E DNA ligases. [PDF]
Nucleic Acids Res, 2018 Williamson A, Grgic M, Leiros HS.
europepmc +1 more source
Biological Activities of Galanthus fosteri Extracts: First Demonstration of the Interaction between Chlorogenic Acid and DNA Ligase by Molecular Docking [PDF]
Safiye Elif Korcan +4 more
openalex +1 more source
Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells [PDF]
, 2012 Catherine Le Chalony +6 more
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TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux
Advanced Science, EarlyView.TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang +14 more
wiley +1 more source