Results 171 to 180 of about 79,069 (319)
Biochemical properties of a high fidelity DNA ligase from Thermus species AK16D [PDF]
Janelle Tong, Weiguo Cao, Francis Barany
openalex +1 more source
BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan +13 more
wiley +1 more source
Anna Rita Bizzarri1, Simona Santini1, Emilia Coppari1, Monica Bucciantini2, Silvia Di Agostino3, Tohru Yamada4, Craig W Beattie4, Salvatore Cannistraro11Biophysics and Nanoscience Centre, CNISM, Facoltà di Scienze, Università della ...
Bizzarri AR +7 more
doaj
Changes of DNA Ligase in Developing Rat Brain<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>
Noriko Nakaya +4 more
openalex +1 more source
Thermodynamics of Human DNA Ligase I Trimerization and Association with DNA Polymerase β [PDF]
Emilios K. Dimitriadis +6 more
openalex +1 more source
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu +14 more
wiley +1 more source
Macromolecular crowding allows blunt-end ligation by DNA ligases from rat liver or Escherichia coli.
Steven B. Zimmerman, Barbara H. Pheiffer
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Identification of essential residues in Thermus thermophilus DNA ligase [PDF]
Juan Luo
openalex +1 more source
Disruption of NF‐κB‐Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis
This study reveals a feedback mechanism regulating copper homeostasis, in which copper directly interacts with TAK1 to activate NF‐κB signaling, while NF‐κB transcriptionally suppresses copper transporter (CTR1) expression. These findings highlight a promising therapeutic strategy for breast cancer by combining NF‐κB inhibitors with copper chelators or
Xiaomei Zhang +16 more
wiley +1 more source
A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation
Background The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial genomes, including many disease-causing species.
Jolyn Pan +4 more
doaj +1 more source

