A novel assay for DNA ligase [PDF]
Nucleic Acids Research, 1991 Jamboor K. Vishwanatha, John Goodchild
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STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer
Advanced Science, EarlyView.This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao +20 more
wiley +1 more source
International Journal of Nanomedicine, 2011 Anna Rita Bizzarri1, Simona Santini1, Emilia Coppari1, Monica Bucciantini2, Silvia Di Agostino3, Tohru Yamada4, Craig W Beattie4, Salvatore Cannistraro11Biophysics and Nanoscience Centre, CNISM, Facoltà di Scienze, Università della ...
Bizzarri AR +7 more
doaj
Changes of DNA Ligase in Developing Rat Brain<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>
, 1977 Noriko Nakaya +4 more
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Two Distinct DNA Ligase Activities in Mitotic Extracts of the Yeast Saccharomyces Cerevisiae [PDF]
, 1997 William Ramos +4 more
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Regulation of Neuroinflammation by Microglial DUBA‐IRAK1‐IKKβ Signaling Loop
Advanced Science, EarlyView.The protein levels of deubiquitinating enzyme A (DUBA) are rapidly upregulated in microglia after activation of Toll‐like receptor 4 (TLR4). In turn, DUBA potentiates TLR4‐induced proinflammatory signal transduction in microglia by stabilizing interleukin‐1 receptor activated kinase 1 (IRAK1) through K48 deubiquitination.
Zhenhu Zhu +22 more
wiley +1 more source
Specific Interaction of DNA Polymerase β and DNA Ligase I in a Multiprotein Base Excision Repair Complex from Bovine Testis [PDF]
, 1996 Rajendra Prasad +5 more
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Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Advanced Science, EarlyView.Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves +17 more
wiley +1 more source
A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation
BMC MicrobiologyBackground The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial genomes, including many disease-causing species.
Jolyn Pan +4 more
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Identification of essential residues in Thermus thermophilus DNA ligase [PDF]
, 1996 Juan Luo
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