Results 241 to 250 of about 77,898 (323)

Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm

open access: gold, 2000
Youngsoo Lee   +3 more
openalex   +1 more source

A Charge‐Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
DNA gel bandage (DNAgb) is designed to precisely target the site of inflammation of IBD, by achieving dual specific localization of inflamed mucosa through electrostatic interactions and ApITGA4‐mediated affinity targeting. DNAgb effectively the activation of inflammatory pathways and reshapes the immune microenvironment.
Peifen Lu   +9 more
wiley   +1 more source

Nonperiodic Activity of the Human Anaphase-Promoting Complex–Cdh1 Ubiquitin Ligase Results in Continuous DNA Synthesis Uncoupled from Mitosis

open access: green, 2000
Claus Storgaard Sørensen   +5 more
openalex   +1 more source

Biomolecular Interaction Prediction: The Era of AI

open access: yesAdvanced Science, EarlyView.
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley   +1 more source

K29‐Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response

open access: yesAdvanced Science, EarlyView.
Under endoplasmic reticulum stress, cells activate the unfolded protein response (UPR). During the UPR, the cohesin complex at the promoter of cell proliferation‐related genes undergoes K29‐linked ubiquitination, recruiting the cohesin release factor WAPL to release cohesin, leading to transcriptional downregulation and inhibition of cell growth ...
Qiushuang Zhang   +5 more
wiley   +1 more source

A Brief Overview of the Epigenetic Regulatory Mechanisms in Plants. [PDF]

open access: yesInt J Mol Sci
Tresas T   +3 more
europepmc   +1 more source

A DNA Ligase from a Hyperthermophilic Archaeon with Unique Cofactor Specificity

open access: green, 2000
Masaru Nakatani   +3 more
openalex   +1 more source

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