Results 181 to 190 of about 2,394,908 (263)

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

open access: yesCytometry Part B: Clinical Cytometry, Volume 110, Issue 6, Page 427-439, November 2026.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana   +3 more
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu   +2 more
wiley   +1 more source

Dynamic Operations in Macromolecular Data Storage

open access: yesAngewandte Chemie, Volume 138, Issue 44, 26 October 2026.
With the exponential growth of digital data and the limitations of conventional silicon‐based storage and computing technologies, macromolecular data storage, the practice of encoding digital information within large, complex molecules like DNA or synthetic polymers, has emerged as a scalable and sustainable alternative to traditional digital ...
Jakub Ossowski   +3 more
wiley   +2 more sources

Substituent‐Guided Routing in Chemical Reaction Networks

open access: yesChemSystemsChem, Volume 8, Issue 6, November 2026.
Substituents act as molecular traffic directors, routing EDC‐fueled oligoesterification either into a constrained reversible dimer loop or through an interconnected, scrambling‐enabled network of higher oligomers. ABSTRACT Metabolism is a complex chemical reaction network (CRN) that distributes reaction flux across multiple pathways, and mimicking such
Yeonsoo Lim   +7 more
wiley   +1 more source

Enzyme-driven triplex structure-based DNA logic circuits. [PDF]

open access: yesJ Nanobiotechnology
Liu X   +14 more
europepmc   +1 more source

Building Molecular Gates with Nucleic Acid Secondary Structures

open access: yes
embargoed_20260918Biological systems, at their foundations, use mechanisms that resemble Boolean functions. ON-OFF molecular switches, dose-response actuators, or concentration-dependent biomolecular complex formation behave according to signal ...
RAZAVI, ATEFEHSADAT
core  

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