Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley +1 more source
Soft Iontronic Diodes: Materials, Mechanisms, and Progress. [PDF]
Li L, Meng Q, Wang L.
europepmc +1 more source
From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui +5 more
wiley +1 more source
Growth control as a central regulator for tuning the cellular context. [PDF]
Hueso-Gil Á +2 more
europepmc +1 more source
Electronic XOR logic gate based on DNA
openaire +1 more source
Synthetic promoter design in plants: integration of computational and experimental approaches. [PDF]
Yaschenko AE, Alonso JM, Stepanova AN.
europepmc +1 more source
Orthogonal recognition of miRNA and lncRNA enables high-fidelity cancer diagnostics. [PDF]
Guo Y +7 more
europepmc +1 more source
Metal‐Ion Regulated Light‐Free Z→E Isomerization of Azobenzene Glycomacrocycle
Metal ion‐catalyzed Z→E isomerization of photoswitchable azobenzene glycomacrocycle: A new azobenzene‐based glycomacrocycle is capable of forming a 1:1 complex with divalent metal ions in both E‐ and Z‐isomers. The complexes undergo light‐free Z→E isomerization in a timescale spanning from seconds to weeks.
Yang Zhou +4 more
wiley +1 more source
Boolean Logic-Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery. [PDF]
Ross ML +3 more
europepmc +1 more source
Intelligent molecular logic computing toolkits: nucleic acid-based construction, functionality, and enhanced biosensing applications. [PDF]
Hu Y +5 more
europepmc +1 more source

