Results 191 to 200 of about 29,739 (230)

Circular DNA Logic Gates with Strand Displacement

Langmuir, 2009
Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring.
Cheng, Zhang, Jing, Yang, Jin, Xu
openaire   +2 more sources

Antibody Activation using DNA‐Based Logic Gates

Angewandte Chemie International Edition, 2015
AbstractOligonucleotide‐based molecular circuits offer the exciting possibility to introduce autonomous signal processing in biomedicine, synthetic biology, and molecular diagnostics. Here we introduce bivalent peptide–DNA conjugates as generic, noncovalent, and easily applicable molecular locks that allow the control of antibody activity using toehold‐
Brian M. G. Janssen, Martijn van Rosmalen, Lotte van Beek, Maarten Merkx   +3 more
openaire   +2 more sources

DNA Sequential Logic Gate Using Two-Ring DNA

ACS Applied Materials & Interfaces, 2016
Sequential DNA detection is a fundamental issue for elucidating the interactive relationships among complex gene systems. Here, a sequential logic DNA gate was achieved by utilizing the two-ring DNA structure, with the ability to recognize "before" and "after" triggering sequences of DNA signals.
Cheng, Zhang, Linjing, Shen, Chao, Liang, Yafei, Dong, Jing, Yang, Jin, Xu   +5 more
openaire   +2 more sources

A DNA based molecular logic gate capable of a variety of logical operations

Natural Computing, 2013
In this paper we report on a module in the RTRACS (Reverse-transcription and TRanscription-based Autonomous Computing System) molecular computing system, constructed with DNA, RNA and enzymes. The module is a 2-input logic gate that receives input and produces output in the form of RNA molecules.
Anton Kan, Yoko Sakai, Ko-ichiroh Shohda, Akira Suyama   +3 more
openaire   +1 more source

Photonic boolean logic gates based on DNA aptamers

Chem. Commun., 2007
We designed a pair of DNA-based logic gates that sense single-stranded DNAs and aptamer ligands to produce fluorescence outputs according to Boolean logic functions AND and OR.
Wataru, Yoshida, Yohei, Yokobayashi
openaire   +2 more sources

DNA-Based Photonic Logic Gates:  AND, NAND, and INHIBIT

Journal of the American Chemical Society, 2002
Conventional microprocessors use elementary logic gates to perform complex computational tasks. Mimicking such computational processes using purely molecular systems has been limited in most cases by the lack of design generality or potential addressability of existing molecular logic gates.
Alan, Saghatelian, Nicolas H, Völcker, Kevin M, Guckian, Victor S-Y, Lin, M Reza, Ghadiri   +4 more
openaire   +3 more sources

Reversible OR Logic Gate Design Using DNA

2012
In today’s world DNA technology is promoted as an alternative approach for advancement over silicon technology. The DNA technology is also used to detect diseases. It needs some molecular computation for which the development of basic circuit unit is required. Basic circuit comprises the AND, OR and NOT gate. In this paper we proposed the design of two-
Pradipta Roy, Debarati Dey, Swati Sinha, Debashis De   +3 more
openaire   +1 more source

Construction of Molecular Logic Gates with a DNA‐Cleaving Deoxyribozyme

Angewandte Chemie, 2006
Shanghai Jiao Tong Univ, BioX Life Sci Res Ctr, Shanghai 200030, Peoples R China; Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China; Tianjin Univ Sci & Technol, Tianjin 300040, Peoples R ...
Xi, Chen, Yifei, Wang, Qiang, Liu, Zhizhou, Zhang, Chunhai, Fan, Lin, He   +5 more
openaire   +2 more sources

DNA Logic Gates Integrated on DNA Substrates in Molecular Computing

ChemBioChem
AbstractDue to nucleic acid's programmability, it is possible to realize DNA structures with computing functions, and thus a new generation of molecular computers is evolving to solve biological and medical problems. Pioneered by Milan Stojanovic, Boolean DNA logic gates created the foundation for the development of DNA computers. Similar to electronic
Andrea C. Bardales, Viktor Smirnov, Katherine Taylor, Dmitry M. Kolpashchikov   +3 more
openaire   +2 more sources

Molecular Logic Gates on DNA Origami Nanostructures for MicroRNA Diagnostics

Analytical Chemistry, 2014
Molecular computing holds great promise for diagnosis and treatment of diseases at the molecular level; nevertheless, designing molecular logic gates to operate programmably and autonomously for molecular diagnostics still remains challenging. We designed logic gates on DNA Origami for microRNA analysis.
Dongfang, Wang, Yanming, Fu, Juan, Yan, Bin, Zhao, Bin, Dai, Jie, Chao, Huajie, Liu, Dannong, He, Yi, Zhang, Chunhai, Fan, Shiping, Song   +10 more
openaire   +2 more sources