Results 131 to 140 of about 2,768,548 (336)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

DNA Methylation, Isocitrate Dehydrogenase Mutation, and Survival in Glioma [PDF]

open access: bronze, 2010
Brock C. Christensen   +11 more
openalex   +1 more source

Development of DNA methylation‐based epigenetic age predictors in loblolly pine ( Pinus taeda ) [PDF]

open access: hybrid, 2022
Steven T. Gardner   +5 more
openalex   +1 more source

Sensitivity of transcription factors to DNA methylation

open access: yesEssays in Biochemistry, 2019
Dynamic binding of transcription factors (TFs) to regulatory elements controls transcriptional states throughout organism development. Epigenetics modifications, such as DNA methylation mostly within cytosine-guanine dinucleotides (CpGs), have the ...
Éléa Héberlé, A. Bardet
semanticscholar   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

open access: yesAdvanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen   +13 more
wiley   +1 more source

Serotonergic brain signatures of peripheral serotonin transporter gene DNA methylation

open access: gold, 2023
S.E.P. Bruzzone   +5 more
openalex   +1 more source

Role of TET enzymes in DNA methylation, development, and cancer

open access: yesGenes & Development, 2016
Ten eleven translocation (TET) genes, and especially TET2, are frequently mutated in various cancers, but how the TET proteins contribute to the onset and maintenance of these malignancies is largely unknown. In this review, Rasmussen and Helin highlight
K. D. Rasmussen, K. Helin
semanticscholar   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Identification of DNA methylation prognostic signature of acute myelocytic leukemia.

open access: yesPLoS ONE, 2018
BackgroundThe aim of this study is to find the potential survival related DNA methylation signature capable of predicting survival time for acute myelocytic leukemia (AML) patients.MethodsDNA methylation data were downloaded.
Haiguo Zhang   +6 more
doaj   +1 more source

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