Results 161 to 170 of about 2,729,754 (384)

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang   +14 more
wiley   +1 more source

Interactions Between Active Matters and Endogenous Fields

open access: yesAdvanced Materials, EarlyView.
This review synthesizes endogenous field information and computational methods in contexts such as cancer, wounds, and biofilms. It organizes NAMs and AAMs by sensing, transmitting, and executing functions, compares their limitations, and from these contrasts proposes design strategies for next‐generation AAMs, offering perspectives to foster ...
Jinwei Lin   +6 more
wiley   +1 more source

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

open access: yesAdvanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad   +3 more
wiley   +1 more source

Fabrication of Multimodal Anion Exchange Membrane for Chromatographic Purification of Full Adeno‐Associated Viral Capsids

open access: yesAdvanced Materials Interfaces, EarlyView.
A novel multi‐modal anion exchange membrane (MMAEX) is successfully fabricated for separating empty and full AAV2 capsids. The functionalized membrane has an average pore size of 0.5 µm and exhibits both charge and hydrophobic functionality. A full capsid recovery of 72.9% at 85.3% purity with gradient elution, or 70.3% recovery at 92.2% purity with ...
Xiaolei Hao   +2 more
wiley   +1 more source

DNA methylation in melanoma immunotherapy: mechanisms and therapeutic opportunities

open access: yesClinical Epigenetics
Abnormal DNA methylation is a hallmark of cancer and a nearly universal feature of melanoma. DNA methylation plays well-appreciated melanoma cell-intrinsic roles, including silencing tumor-suppressor genes, regulating genomic stability, deregulating ...
Maya G. Deshmukh   +5 more
doaj   +1 more source

Chemical Methylation of RNA and DNA Viral Genomes as a Probe of In Situ Structure [PDF]

open access: bronze, 1981
Minoru Yamakawa   +2 more
openalex   +1 more source

Advanced Materials in Responsible Electronics: Innovations for Sustainability, Health, and Circularity

open access: yesAdvanced Materials Technologies, EarlyView.
Contemporary electronic devices produce significant waste, harming ecosystems. Innovation in design, consumption, materials, and end‐of‐life management is crucial. This review explores advanced materials for sustainable and responsible electronics, highlighting their potential to reduce environmental and health hazards while improving device ...
Rawan Omar   +7 more
wiley   +1 more source

Methylation of Replicating and Nonreplicating DNA in the Ciliate \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]

open access: yes, 1989
Methylation of adenine in replicating and nonreplicating DNA of the ciliate Tetrahymena thermophila was examined. In growing cells, 87% of the methylation occurred on the newly replicated daughter strand, but methylation was also detectable on the ...
Harrison, Gail Singer   +1 more
core   +1 more source

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