Results 271 to 280 of about 2,686,549 (398)

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source

DNA Methylation Occurred around Lowly Expressed Genes of Plastid DNA during Tomato Fruit Development

, 1988
Jarunya Ngernprasirtsiri, Hirokazu Kobayashi, Takashi Akazawa   +2 more
openalex   +2 more sources

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Characterization of DNA Methylation Episignatures for Radon-Induced Lung Cancer. [PDF]

Int J Mol Sci
Yan Z, Chen H, Liu Y, Zhou L, Zhu J, Hou Y, Zhang X, Chen Z, Wang Y, Zhou PK, Gu Y.   +10 more
europepmc   +1 more source

Tissue- and cell-specific casein gene expression. II. Relationship to site-specific DNA methylation.

, 1983
M L Johnson, Joseph Levy, Scott C. Supowit, Li‐Yuan Yu‐Lee, Jeffrey M. Rosen   +4 more
openalex   +1 more source

CpG methylation directly inhibits binding of the human papillomavirus type 16 E2 protein to specific DNA sequences [PDF]

, 1996
Alison Thain, Owen Jenkins, Alan R. Clarke, Kevin Gaston   +3 more
openalex   +1 more source

DNA Methylation

, 2015
Alokail, Majed S., Alenad, Amal M.
openaire   +3 more sources

Capsaicin Alleviates Autophagy‐Lysosomal Dysfunction via PPARA‐Mediated V‐ATPase Subunit ATP6V0E1 Signaling in 3xTg‐AD Mice

Advanced Science, EarlyView.
Capsaicin enhances lipid metabolism, reduces lipid deposition, and alleviates AD‐related pathologies. Capsaicin activates PPARA, promoting the expression of PPAR signaling pathway‐related genes and accelerating lipid metabolism. Capsaicin upregulates ATP6V0E1‐V‐ATPase‐mediated lysosomal acidification, enhancing lipid droplet clearance. PPARA is the key
Haitao Yu, Jia Chen, Fangzhou Wang, Dongdong Jia, Shuguang Bi, Yuming Mao, Yu‐qi Zhang, Tian‐long Gao, Liu Yang, Jia‐xu Du, Zi‐han Zhou, Xi‐Chen Zhu, Gao‐shang Chai   +12 more
wiley   +1 more source

DNA Methylation in Long-Term Memory. [PDF]

Physiology (Bethesda)
Chen X, Peng Y, Liu XS.
europepmc   +1 more source

Tandem B1 Elements Located in a Mouse Methylation Center Provide a Target for de Novo DNA Methylation [PDF]

, 1999
Phillip A. Yates, Robert Burman, Padmaja Mummaneni, Sandra Krussel, Mitchell S. Turker   +4 more
openalex   +1 more source