Results 191 to 200 of about 267,722 (305)

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Sleep patterns and DNA methylation age acceleration in middle-aged and older Chinese adults. [PDF]

Clin Epigenetics
Diao T, Liu K, Zhou L, Wang Q, Lyu J, Zhu Z, Chen F, Qin W, Yang H, Wang C, Zhang X, Wu T.   +11 more
europepmc   +1 more source

DNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva cohort. [PDF]

Clin Epigenetics, 2023
Bozack AK, Rifas-Shiman SL, Gold DR, Laubach ZM, Perng W, Hivert MF, Cardenas A.   +6 more
europepmc   +1 more source

Serum PFAS in Aircraft Rescue and Firefighting (ARFF) Firefighters From Six U.S. Airport Fire Departments

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Use of aqueous film‐forming foam (AFFF) is a source of exposure to per‐ and polyfluoroalkyl substances (PFAS) for firefighters working in aircraft rescue and firefighting (ARFF) settings. However, data characterizing the association between serum PFAS concentrations and exposure risk factors for ARFF firefighters are limited ...
Miriam M. Calkins, Yiwen Liu, Gavin Horn, Antonia M. Calafat, Judith M. Graber, Shawn C. Beitel, Alberto J. Caban‐Martinez, Julianne Cook Botelho, Randy Krause, Rob Mathis, Jeff Hughes, Casey Grant, Jaclyn M. Goodrich, Amy Nematollahi, Alesia M. Jung, Alissa D. Coleman, Sally Littau, Brooke A. Hawkes, Alexander C. Mayer, Jefferey L. Burgess   +19 more
wiley   +1 more source

DNA methylation age acceleration is associated with incident cognitive impairment in the health and retirement study. [PDF]

J Alzheimers Dis
Blostein F, Bakulski KM, Fu M, Wang H, Zawistowski M, Ware EB.   +5 more
europepmc   +1 more source

DNA methylation in senescence, aging and cancer

Oncoscience, 2019
Xie, Wenbing, Baylin, Stephen B., Easwaran, Hariharan   +2 more
openaire   +2 more sources

Rapid Genome and Exome Sequencing in Inpatients: Clinical Impact at a Tertiary Academic Medical Center

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The objective of this study is to describe outcomes of rapid exome (rES) and rapid genome sequencing (rGS) in an inpatient setting. This is a retrospective cohort of inpatients with rES or rGS during their hospitalization between April 2016 and November 2023.
Cecilia M. Kessler, Bryce A. Schuler, Elizabeth A. Jasper, Janet Talbert, Laura Duncan, Mackenzie Mosera   +5 more
wiley   +1 more source

Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study. [PDF]

Aging (Albany NY)
Li Z, Ding H, Wang M, Li Y, Ang TFA, Ashita G, Gifford KA, Karjadi C, Levy D, Au R, Liu C.   +10 more
europepmc   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

Second generation DNA methylation age predicts cognitive change in midlife: the moderating role of childhood socioeconomic status. [PDF]

Aging (Albany NY)
Bell SA, Beam CR, Zandi E, Kam A, Andrews E, Becker J, Finkel D, Davis DW, Turkheimer E.   +8 more
europepmc   +1 more source