Results 161 to 170 of about 2,516,689 (307)

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

Proceedings of the National Academy of Sciences of the United States of America, 2000
B. Ramsahoye, D. Biniszkiewicz, F. Lyko, Victoria H. Clark, A. Bird, R. Jaenisch   +5 more
semanticscholar   +1 more source

Role of non-coding RNAs in O⁶-methylguanine-DNA methyltransferase-positive glioblastoma (Review). [PDF]

Oncol Lett
Guo Y, Guo J, Xiao W, Lu Y.
europepmc   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

"Two scoops, please!": Twin cryo-EM structures of an Arabidopsis thaliana DNA methyltransferase. [PDF]

Plant Cell
Hübbers JW.
europepmc   +1 more source

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source

Epigenetic regulation of macrophage polarization by DNA methyltransferase 3b.

Molecular Endocrinology, 2014
Xiaosong Yang, Xian-feng Wang, Dongxu Liu, Liqing Yu, B. Xue, Hang Shi   +5 more
semanticscholar   +1 more source

Analysis of DNA methyltransferase 3 alpha expression during respiratory syncytial virus strain A infection. [PDF]

Sci Rep
Becker AL, Borges SG, Pinheiro LGR, Nascimento Freitas D, Duarte L, Nunes E, Cassão G, Poppe J, da Silva RP, Castro MS, Fernandes KA, Andrade CF, de Oliveira Espinel J, de Rezende Rodovalho V, Vinolo MAR, Stein RT, de Souza APD.   +16 more
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Wheat DNA Methyltransferase TaMET1 Negatively Regulates Salicylic Acid Biosynthesis to Facilitate Powdery Mildew Susceptibility. [PDF]

J Fungi (Basel)
Ge P, Chen W, Liu J, Wang X, Chang C.
europepmc   +1 more source

First National Expanded Genomic Newborn Screening Program in Qatar; A Pilot Study, Doha‐Heidelberg Collaboration

American Journal of Medical Genetics Part A, EarlyView.
Reem Alsulaiman, Sarah Okashah, Radja Messai Badji, Fatemeh Abbaszadeh, Yaser Alsarraj, Rehab Ali Abdulrahman, Noora Shahbeck, Thalib Moideen, Reema El Hassan, Fatima Al‐Hamaydeh, Einas Alkuwari, Said Ismail, Hilal Al‐ Rifai, Ghassan Abdoh, Christian P. Schaaf, Georg Hoffmann, Saad Al‐Kaabi, Wadha Al‐Muftah, Tawfeg Ben‐Omran   +18 more
wiley   +1 more source