Results 141 to 150 of about 71,628 (244)

Phylogenomics, ecomorphological evolution, and historical biogeography in Deuterocohnia (Bromeliaceae: Pitcairnioideae)

American Journal of Botany, EarlyView.
Abstract Premise Species of Deuterocohnia (17 spp.) show extraordinary variation in elevation (0–3900 m a.s.l.) and growth forms, and many have narrow geographic distributions in the west‐central Andes and the Peru‐Chile coast. Previous research using few plastid and nuclear loci failed to produce well‐resolved or supported phylogenies.
Bing Li, Nicole Schütz, Kurt Weising, Georg Zizka, Jacob B. Landis, Thomas J. Givnish   +5 more
wiley   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Prevalence of DNA Mismatch Repair Deficiencies in Multiple Solid Tumor Types in China. [PDF]

J Evid Based Med
Shi X, Yang X, Yun J, Fan X, Hou Y, Wang Z, Li P, Chen J, Jiang D, Chen L, Wang Y, Ramar R, Wong MT, Poon SL, Liang Z.   +14 more
europepmc   +1 more source

Prostate Cancer Risk and DNA Mismatch Repair Deficiency Among Lynch Syndrome Patients. [PDF]

Eur Urol Open Sci
Rodgers-Fouché L, Kamkari NA, Cruz M, Gusev A, Justiniano SI, Wu CL, Chung DC, Salari K.   +7 more
europepmc   +1 more source

DNA mismatch repair in HIV-Associated Lymphoma: Lost in Translation? [PDF]

Y.L. Jiang, Suling Chen, Muye Xia, Xuwen Xu, Jie Peng, Shaohang Cai   +5 more
openalex   +1 more source

Correspondence on "Deficient DNA mismatch repair and Nectin-4 expression in upper tract urothelial carcinoma (UTUC)". [PDF]

J Cancer Res Clin Oncol
Peker P.
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Immune checkpoint blockade in locally advanced rectal cancer with deficient DNA mismatch repair: retrospective multicenter experience. [PDF]

ESMO Open
Emiloju OE, Foster NR, Shah P, Opneja A, Gupta A, Singh M, Bonneau K, Steinert KO, Saeed A, Strickler JH, Overman MJ, Sinicrope FA.   +11 more
europepmc   +1 more source

Repair of DNA Double-Strand Breaks and Mismatches in Drosophila

, 2001
Carlos C. Flores
openalex   +1 more source

KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: Results from a large international multicentre study [PDF]

, 2013
Nicole C.T. van Grieken, T Aoyma, Philip Chambers, Daniel Bottomley, Lindsay C. Ward, Imran Inam, Tineke E. Buffart, Kakoli Das, T.W. Lim, Brendan Pang, S L Zhang, Iain Beehuat Tan, Beatriz Carvalho, Daniëlle A.M. Heideman, Yohei Miyagi, Y. Kameda, Tomio Arai, Gerrit A. Meijer, Akira Tsuburaya, Patrick Tan, Takaki Yoshikawa, Heike I. Grabsch   +21 more
openalex   +1 more source