Results 131 to 140 of about 72,949 (261)

The GHKL ATPase Family as a Paradigm for MutL Homolog Function in DNA Mismatch Repair. [PDF]

Int J Mol Sci
Piscitelli JM, Manhart CM.
europepmc   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

dMMR killer: A conditional suicide gene that preferentially kills DNA mismatch repair-deficient cells. [PDF]

Mol Ther Nucleic Acids
Saito S, Kato S, Arai U, Tateishi K, Adachi N.   +4 more
europepmc   +1 more source

From Metabolic Crisis to Molecular Classification: Multidisciplinary Management of Synchronous Endometrioid Ovarian and Endometrial Carcinomas With Massive Tumor Burden

Cancer Nexus, EarlyView.
Managing massive tumor burden in synchronous endometrioid carcinomas. The graphical abstract summarizes the clinical pathway from presentation with massive ascites, pleural effusion, and critical metabolic abnormalities to multidisciplinary stabilization, surgical management, integrated morphologic–molecular classification, and shared decision‐making ...
Anna Homeniuk, Leena Abdalla, Sharon Fitzgerald   +2 more
wiley   +1 more source

Prevalence of DNA Mismatch Repair Deficiencies in Multiple Solid Tumor Types in China. [PDF]

J Evid Based Med
Shi X, Yang X, Yun J, Fan X, Hou Y, Wang Z, Li P, Chen J, Jiang D, Chen L, Wang Y, Ramar R, Wong MT, Poon SL, Liang Z.   +14 more
europepmc   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Prostate Cancer Risk and DNA Mismatch Repair Deficiency Among Lynch Syndrome Patients. [PDF]

Eur Urol Open Sci
Rodgers-Fouché L, Kamkari NA, Cruz M, Gusev A, Justiniano SI, Wu CL, Chung DC, Salari K.   +7 more
europepmc   +1 more source

Gas–Solid Interface‐Assisted Growth of Organic Semiconductor Single Crystals: Dimensions, Structures, Mechanisms, and Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Gas–solid interface‐assisted growth strategies have unlocked precise control over crystal structure, morphology, dimension, and molecular packing. The obtained organic semiconductor single crystals represent the ideal candidates for high‐performance organic optoelectronic devices.
Tingyi Yan, Qing Tian, Jinwen Wang, Ke Jiang, Yage Han, Yuanzhuang Ren, Lingyun Li, Xiujuan Zhang, Jiansheng Jie   +8 more
wiley   +1 more source

Molecular Profiling of Germline Variants in the DNA Mismatch Repair Genes in Chinese Colorectal Cancer Patients. [PDF]

Genet Res (Camb)
Zhu X, Han D, Chen J, Xu J, Jin J, Lai Q, Xie L, Fang J, Zhu L, Yu Y, Yang J, Wang T, Xiang X, Shi X, Xiao D, Su D.   +15 more
europepmc   +1 more source

Synthesis of DNA Building Blocks With Aminonaphthalimides and Cyanovinylenes as Uncharged Fluorophores: Fluorescent Readout From Turn‐On to Red‐Shift

European Journal of Organic Chemistry, EarlyView.
DNA architectures with aminonaphthalimides and cyanovinylenes as base surrogates form interstrand and intrastrand dimers showed that can be used as nucleic acid‐sensitive probes by their fluorescence turn‐on and red‐shift as readouts. The fluorescence turn‐on was tested by probing N6‐methyl‐2’‐deoxyadenosine (m6A) in DNA.
Jan Kunzmann, Anna‐Lena Ruopp, Hans‐Achim Wagenknecht   +2 more
wiley   +1 more source