Results 161 to 170 of about 70,351 (245)

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

Clinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz, Eric Farber‐Eger, Marwa Tantawy, Neyousha Shahisavandi, Timothy J. Garrett, Samuel M. Rubinstein, Michael G. Fradley, Mohammed E. Alomar, Danny DeAvila, Kenneth H Shain, R. Frank Cornell, Daniel Lenihan, Qing Lu, Quinn S Wells, Rachid C. Baz, Yan Gong   +15 more
wiley   +1 more source

Nonrepair functions of DNA mismatch repair proteins: new avenues for precision oncology. [PDF]

Trends Cancer
DeWitt JT, Raghunathan M, Haricharan S.
europepmc   +1 more source

Whole tissue imaging of cellular boundaries at sub‐micron resolutions for deep learning cell segmentation: Applications in the analysis of epithelial bending of ectoderm

Developmental Dynamics, EarlyView.
Abstract Background To understand cellular morphology, biologists have relied on traditional optical microscopy of tissues combined with tissue clearing protocols to image structures deep within tissues. Unfortunately, these protocols often struggle to retain cell boundary markers, especially at high enough resolutions necessary for precise cell ...
Sam C. P. Norris, Jimmy K. Hu, Neil H. Shubin   +2 more
wiley   +1 more source

Correlation between Isocitrate Dehydrogenase Mutation and Immunohistochemical Expression of DNA Mismatch Repair Proteins in the Prognosis of Gliomas. [PDF]

Asian Pac J Cancer Prev
Saeed NM, Rashed H, Hussein S, Al-Karamany AS, Elmesallamy W, Waley AB, Obaya AA, Gharieb SA, Amgd K, Ibrahim SM, Abdelhamid MI, Khamis T, Mohamed AH.   +12 more
europepmc   +1 more source

Trends in marine species distribution models: a review of methodological advances and future challenges

Ecography, EarlyView.
Correlative species distribution models (SDMs) are quantitative tools in biogeography and macroecology. Building upon the ecological niche concept, they correlate environmental covariates to species presence to model habitat suitability and predict species distributions.
Moritz Klaassen, Tiago A. Marques, Filipe Alves, Marc Fernandez   +3 more
wiley   +1 more source

DNA Mismatch Repair Gene Mosaicism Is Rare in People With Mismatch Repair-Deficient Cancers. [PDF]

Gastroenterology
Walker R, Joo JE, Mahmood K, Georgeson P, Angels-CCFR-MUIR-Torre Consortium, Winship IM, Buchanan DD.   +6 more
europepmc   +1 more source

Multi‐Dimensional Conductive Nanocomposites for Flexible Electronics

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Multi‐dimensional conductive nanocomposites integrate 0D, 1D, and 2D nanomaterials through spatial structure regulation and interface engineering, achieving “1 + 1 > 2” synergistic effects. By leveraging 0D filling to reduce contact resistance, 1D bridging to construct continuous conductive paths, and 2D supporting to enhance mechanical stability ...
Tianyu Wang, Ruimin Cai, Abbas Ali, Lizhe Li, Li Yang, Hulin Zhang, Xuge Fan, Yumin Xia, Wenyong Lai, Linmao Qian, Tiehu Li, Guosheng Shao, Liang Tian   +12 more
wiley   +1 more source

Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in gastric adenosquamous carcinoma. [PDF]

Virchows Arch
Gu Y, Liu Z, Sheng X, Dong L, Chen C, Xu H, Wang Z, Zhang B, Li Q, Wang Y, Yang Y, Peng Q, Zhu L, Yuan F, Wang C, Li A.   +15 more
europepmc   +1 more source

DNA mismatch repair (MMR) genes expression in lung cancer and its correlation with different clinicopathologic parameters. [PDF]

Sci Rep
Farrag MS, Abdelwahab HW, Abdellateef A, Anber N, Ellayeh MA, Hussein DT, Eldesoky AR, Sheta H.   +7 more
europepmc   +1 more source

Faecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen, Nele M. Korten, Larissa Blischke, Clara Voelz, Cordian Beyer, Jochen Seitz, Stefanie Trinh   +6 more
wiley   +1 more source