Results 161 to 170 of about 71,628 (244)

The DNA mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression. [PDF]

Neoplasia
Brooksbank K, Smith C, Maniati E, Gibson A, Tse WY, Hall AK, Wang J, Sharp TV, Martin SA.   +8 more
europepmc   +1 more source

Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells

Chemistry – A European Journal, EarlyView.
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu, Kunihiko Morihiro, Rui Cong, Samruddhi Maheshwar Patil, Idoia Wille, Akimitsu Okamoto   +5 more
wiley   +1 more source

A Pathological Complete Response After Pembrolizumab for DNA Mismatch Repair-Deficient/Microsatellite Instability-High Colorectal Cancer Enabling Curative Surgery: A Case Report. [PDF]

Cureus
Hanekom BL, Coveney A.
europepmc   +1 more source

Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications

Chemistry – A European Journal, EarlyView.
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley   +1 more source

Somatic Mutations in DNA Mismatch Repair Genes, Mutation Rate and Neoantigen Load in Acute Lymphoblastic Leukemia. [PDF]

Pharmaceuticals (Basel)
Mendiola-Soto DK, Gómez-Romero L, Núñez-Enríquez JC, Flores-Lujano J, Jiménez-Hernández E, Medina-Sansón A, Bekker-Méndez VC, Mata-Rocha M, Pérez-Saldívar ML, Duarte-Rodríguez DA, Torres-Nava JR, Peñaloza-González JG, Flores-Villegas LV, Amador-Sánchez R, Velázquez-Aviña MM, Martín-Trejo JA, Merino-Pasaye LE, Solís-Labastida KA, Espinosa-Elizondo RM, Pérez-Amado CJ, May-Hau DI, Sepúlveda-Robles OA, Rosas-Vargas H, Mejía-Aranguré JM, Jiménez-Morales S.   +24 more
europepmc   +1 more source

Evaluation of DNA Mismatch Repair Proteins by Immunohistochemistry Using Two Antibodies

Leonardo S. Lino-Silvca, Mariana Salazar-Castillo, Scarlett F. Balderas-López, Sabrina B. Martínez-Villavicencio, Luisa F. Rivera-Moncada, Hanna I Ortega-Martínez, César Zepeda‐Najar   +6 more
openalex   +2 more sources

Supplementary Table 2 from GLI1 Interferes with the DNA Mismatch Repair System in Pancreatic Cancer through BHLHE41-Mediated Suppression of MLH1

, 2023
Shingo Inaguma, Miho Riku, Mitsuyoshi Hashimoto, Hideki Murakami, Shinsuke Saga, Hiroshi Ikeda, Kenji Kasai   +6 more
openalex   +1 more source

Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

Chemistry – A European Journal, EarlyView.
Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley   +1 more source

Supplementary Data from MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma

, 2023
Tian Gan, Yan Wang, Manyi Xie, Qiang Wang, Saisai Zhao, Peng Wang, Qinyu Shi, Xuanchen Qian, Faan Miao, Zhigang Shen, Er Nie   +10 more
openalex   +1 more source

In Vitro Live Cell Imaging Reveals Nuclear Dynamics and Role of the Cytoskeleton During Asymmetric Division of Pollen Mitosis I in Nicotiana Benthamiana

Cytoskeleton, EarlyView.
ABSTRACT Pollen is a male gametophyte of angiosperms. Following meiosis, the microspore undergoes an asymmetric division called pollen mitosis I (PMI), which produces two cells of different sizes: a large vegetative cell and a small generative cell. Polarized nuclear migration and positioning during PMI are important for successful pollen development ...
Yoko Mizuta, Masako Igarashi, Tomomi Shinagawa, Ikuma Kaneshiro, Haoto Anan, Daisuke Kurihara   +5 more
wiley   +1 more source