Results 181 to 190 of about 129,123 (307)

Deficient DNA mismatch repair and Nectin-4 expression in upper tract urothelial carcinoma (UTUC). [PDF]

J Cancer Res Clin Oncol
Duan P, Yu L, Hao Y, Deng S, Hong P, Lu M, Zhang S.   +6 more
europepmc   +1 more source

Tetramerization of the DNA mismatch repair protein MutS enhances daughter strand incision preferentially in the vicinity of replication errors. [PDF]

J Biol Chem
Mardenborough Y, van Genderen RM, Laffeber C, de Koning KDA, Friedhoff P, Kanaar R, Depken M, Lebbink JHG.   +7 more
europepmc   +1 more source

The role of DNA mismatch repair mutS/mutL homolog genes in spermatogenesis and male infertility: a systematic review and cohort study. [PDF]

Reprod Biol Endocrinol
Podgrajsek R, Hodzic A, Maver A, Stimpfel M, Andjelic A, Miljanovic O, Ristanovic M, Novakovic I, Plaseska-Karanfilska D, Noveski P, Ostojic S, Buretic-Tomljanovic A, Peterlin B.   +12 more
europepmc   +1 more source

Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing.
Kyle M. Roddick, Elias B. Habib, Richard E. Brown, Fuat Balcı   +3 more
wiley   +1 more source

The DNA mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression. [PDF]

Neoplasia
Brooksbank K, Smith C, Maniati E, Gibson A, Tse WY, Hall AK, Wang J, Sharp TV, Martin SA.   +8 more
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz, Anna‐Lena Drommershausen, Alexander Grünberger, Dirk Holtmann   +3 more
wiley   +1 more source

Somatic Mutations in DNA Mismatch Repair Genes, Mutation Rate and Neoantigen Load in Acute Lymphoblastic Leukemia. [PDF]

Pharmaceuticals (Basel)
Mendiola-Soto DK, Gómez-Romero L, Núñez-Enríquez JC, Flores-Lujano J, Jiménez-Hernández E, Medina-Sansón A, Bekker-Méndez VC, Mata-Rocha M, Pérez-Saldívar ML, Duarte-Rodríguez DA, Torres-Nava JR, Peñaloza-González JG, Flores-Villegas LV, Amador-Sánchez R, Velázquez-Aviña MM, Martín-Trejo JA, Merino-Pasaye LE, Solís-Labastida KA, Espinosa-Elizondo RM, Pérez-Amado CJ, May-Hau DI, Sepúlveda-Robles OA, Rosas-Vargas H, Mejía-Aranguré JM, Jiménez-Morales S.   +24 more
europepmc   +1 more source

A Pathological Complete Response After Pembrolizumab for DNA Mismatch Repair-Deficient/Microsatellite Instability-High Colorectal Cancer Enabling Curative Surgery: A Case Report. [PDF]

Cureus
Hanekom BL, Coveney A.
europepmc   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source