Causes of DNA mismatch repair deficiency in sebaceous skin lesions demonstrating loss of MLH1 protein expression: constitutional over somatic MLH1 promoter methylation. [PDF]
Joo JE +9 more
europepmc +1 more source
ABSTRACT The accelerating pace of urban expansion has profoundly reshaped urban–rural ecosystems, altering soil environments and impairing key ecological services. However, the combined impacts of urban expansion and atmospheric nitrogen (N) deposition on soil multifunctionality—the capacity to sustain multiple ecological processes—remain poorly ...
Xu Sun +3 more
wiley +1 more source
DNA mismatch repair deficiency in conjunctival melanoma. [PDF]
Rodriguez A, Moser J, Ramasubramanian A.
europepmc +1 more source
Abstract Assigning taxonomic identity and thus assessing taxonomic diversity in gelatinous zooplankton is challenging due to their fragility and difficult preservation. Formalin fixation compromises DNA integrity, while flash‐freezing, ethanol, and acetone preservation affect morphological features. In this study, we developed a methodological protocol
Claudia Traboni +4 more
wiley +1 more source
Neoadjuvant immunotherapy for DNA mismatch repair proficient/microsatellite stable non-metastatic rectal cancer: a systematic review and meta-analysis. [PDF]
Zhang H +6 more
europepmc +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Dissecting DNA-mismatch-repair-driven mutational processes in human cells
Owusu M +4 more
europepmc +1 more source
Mycobacterium smegmatis NucS-promoted DNA mismatch repair involves limited resection by a 5'-3' exonuclease and is independent of homologous recombination and NHEJ. [PDF]
Rivera-Flores IV, Wang EX, Murphy KC.
europepmc +1 more source
Replication fork stalling in late S-phase elicits nascent strand degradation by DNA mismatch repair. [PDF]
Colicino-Murbach E +2 more
europepmc +1 more source
Combining single-molecule and structural studies reveals protein and DNA conformations and assemblies that govern DNA mismatch repair. [PDF]
Erie DA, Weninger KR.
europepmc +1 more source

