Results 191 to 200 of about 2,120,704 (297)

Tetramerization of the DNA mismatch repair protein MutS enhances daughter strand incision preferentially in the vicinity of replication errors. [PDF]

J Biol Chem
Mardenborough Y, van Genderen RM, Laffeber C, de Koning KDA, Friedhoff P, Kanaar R, Depken M, Lebbink JHG.   +7 more
europepmc   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Nivolumab plus ipilimumab and cobimetinib in previously treated microsatellite-stable/DNA mismatch repair-proficient metastatic colorectal cancer: the phase II CheckMate 142 trial. [PDF]

ESMO Gastrointest Oncol
Overman MJ, McCraith S, He B, Jin L, Lei M, Yao J, Morse MA.   +6 more
europepmc   +1 more source

Estuarine benthic diversity declines with temperature across a tropical–temperate gradient

Ecography, EarlyView.
Estuarine benthic sediments are important habitats that support ecosystem health and productivity, but the drivers of large‐scale patterns in benthic diversity are not well documented. Using 18S amplicon sequencing of 425 sediment DNA samples from estuaries spanning 20° of latitude along Australia's east coast, we assessed tropical–temperate patterns ...
Sally A. Bracewell, Mariana Mayer‐Pinto, Katherine A. Dafforn, Sebastian Vadillo Gonzalez, Thayanne L. Barros, Emma L. Johnston   +5 more
wiley   +1 more source

The role of DNA mismatch repair mutS/mutL homolog genes in spermatogenesis and male infertility: a systematic review and cohort study. [PDF]

Reprod Biol Endocrinol
Podgrajsek R, Hodzic A, Maver A, Stimpfel M, Andjelic A, Miljanovic O, Ristanovic M, Novakovic I, Plaseska-Karanfilska D, Noveski P, Ostojic S, Buretic-Tomljanovic A, Peterlin B.   +12 more
europepmc   +1 more source

Gas–Solid Interface‐Assisted Growth of Organic Semiconductor Single Crystals: Dimensions, Structures, Mechanisms, and Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Gas–solid interface‐assisted growth strategies have unlocked precise control over crystal structure, morphology, dimension, and molecular packing. The obtained organic semiconductor single crystals represent the ideal candidates for high‐performance organic optoelectronic devices.
Tingyi Yan, Qing Tian, Jinwen Wang, Ke Jiang, Yage Han, Yuanzhuang Ren, Lingyun Li, Xiujuan Zhang, Jiansheng Jie   +8 more
wiley   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

The DNA mismatch repair protein, MSH6 is a novel regulator of PD-L1 expression. [PDF]

Neoplasia
Brooksbank K, Smith C, Maniati E, Gibson A, Tse WY, Hall AK, Wang J, Sharp TV, Martin SA.   +8 more
europepmc   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

Exploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang, Yi Yang, Heng Li, Xiaolin Hu, Hui Xiao, Dou Wang, Sergio Benardini, Wei Gu, Yang Luo   +8 more
wiley   +1 more source

Somatic Mutations in DNA Mismatch Repair Genes, Mutation Rate and Neoantigen Load in Acute Lymphoblastic Leukemia. [PDF]

Pharmaceuticals (Basel)
Mendiola-Soto DK, Gómez-Romero L, Núñez-Enríquez JC, Flores-Lujano J, Jiménez-Hernández E, Medina-Sansón A, Bekker-Méndez VC, Mata-Rocha M, Pérez-Saldívar ML, Duarte-Rodríguez DA, Torres-Nava JR, Peñaloza-González JG, Flores-Villegas LV, Amador-Sánchez R, Velázquez-Aviña MM, Martín-Trejo JA, Merino-Pasaye LE, Solís-Labastida KA, Espinosa-Elizondo RM, Pérez-Amado CJ, May-Hau DI, Sepúlveda-Robles OA, Rosas-Vargas H, Mejía-Aranguré JM, Jiménez-Morales S.   +24 more
europepmc   +1 more source