Results 191 to 200 of about 72,949 (261)

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source

Double-Strand Breaks Induce Nuclear-Cytosolic Shuttling of Polymorphic DNA Mismatch Repair Protein MutS Homolog 3 and Binding to NEMO/IKKγ in Colon Cancer Cells. [PDF]

Gastro Hep Adv
Tseng-Rogenski SS, Koi M, Carethers JM.
europepmc   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

The Relationship Between DNA Mismatch Repair Status and Clinicopathologic Characteristics in Colon Cancer. [PDF]

Turk J Gastroenterol
Doğan M, Kılıç M, Tatlı Doğan H.
europepmc   +1 more source

Demographic and Clinical Characteristics of Early‐Onset Colorectal Cancer in Sweden and Finland: A Multicentre Retrospective Cohort Study Over Three Decades

Journal of Surgical Oncology, EarlyView.
ABSTRACT Colorectal cancer is the third most common cancer worldwide, and the proportion of individuals diagnosed under the age of 50 years, referred to as early‐onset colorectal cancer (EOCRC), is increasing. The aim of this study was to evaluate how the demographic and clinical features of EOCR in northern Sweden and Finland have changed over time ...
Melina Charalambidi, Tanja Hukkinen, Tuomas Kaprio, Sofia Edin, Mats Hjortborg, Cecilia Williams, Jaana Hagström, Caj Haglund, Richard Palmqvist, Karin Strigård, Camilla Böckelman, Ioannis Gkekas   +11 more
wiley   +1 more source

Alcohol and colorectal cancer risk, subclassified by mutational signatures of DNA mismatch repair deficiency. [PDF]

J Natl Cancer Inst
Fang A, Ugai T, Gurjao C, Zhong R, Liu Z, Zhang X, Wang P, Nowak J, Wang M, Giannakis M, Ogino S, Zhang X, Giovannucci E.   +12 more
europepmc   +1 more source

Cougar density on the Oregon Coast: Using dead recovery modeling in an open population

The Journal of Wildlife Management, EarlyView.
The primary objective of this study was to determine cougar density in western Oregon. Our results demonstrate that integrating DNA collected via bio‐darting, mandatory hunter‐harvest check‐ins, and GPS collar data into the OPCR2 is a reliable method for estimating cougar densities in densely forested coastal systems.
Jason A. Kirchner, Joel S. Ruprecht, Jennifer R. Adams, Lisette P. Waits, Gregory C. Reed   +4 more
wiley   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

The structure of the MutL-CTD:processivity-clamp complex provides insight regarding strand discrimination in non-methyl-directed DNA mismatch repair. [PDF]

Nucleic Acids Res
Nirwal S, Jha R, Narayanan N, Sharma M, Kulkarni DS, Sharma D, Babu AS, Suthar DK, Rao DN, Nair DT.   +9 more
europepmc   +1 more source

Underground Lag: Fungal Community and Edaphic Legacies After Disturbance

Land Degradation &Development, EarlyView.
ABSTRACT Páramos are neotropical mountain ecosystems that regulate water and store large amounts of carbon, but are increasingly degraded by agriculture and grazing. Although native vegetation often recolonizes after abandonment, belowground recovery remains poorly understood.
Wilmer Dajhan Navarrete‐López, Arantzazu Molins, María Elena Solarte, Camila Enriquez‐Paz, Joshua Borràs, Josefina Bota, Elena Baraza   +6 more
wiley   +1 more source