Results 201 to 210 of about 875,099 (273)

Structural basis of multitasking by the apicoplast DNA polymerase fromPlasmodium falciparum

Kumari A, Enache T, Craggs TD, Pata JD, Lahiri I.   +4 more
europepmc   +1 more source

A robust strategy for overexpression of DNA polymerase from Thermus aquaticus using an IPTG-independent autoinduction system in a benchtop bioreactor. [PDF]

Sci Rep
Laksmi FA, Lischer K, Nugraha Y, Violando WA, Helbert, Nuryana I, Khasna FN, Nur N, Ramadhan KP, Tobing DAL, Hariyatun, Hidayat I.   +11 more
europepmc   +1 more source

Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion

Advanced Science, EarlyView.
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen, Zongwei Li, Zhihong Fang, Zou Li, Daoyan Yang, Yuan Li, Shurong Liu, Zhiqiang Liu, Rui Liu, Huan Liu   +9 more
wiley   +1 more source

DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins

Xu L, Jin S, Urem M, Lee S, Lamers MH, Chen X, Wolynes P, Wuite GJL.   +7 more
europepmc   +1 more source

The mutational landscape of Bacillus subtilis conditional hypermutators shows how proofreading skews DNA polymerase error rates. [PDF]

Nucleic Acids Res
Tanneur I, Dervyn E, Guérin C, Kon Kam King G, Jules M, Nicolas P.   +5 more
europepmc   +1 more source

DNA-Dependent DNA Polymerases I and II from Normal Human-Blood Lymphocytes

, 1972
R. Graham Smith, Robert C. Gallo
openalex   +1 more source

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

Advanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Minchun Zhang, Zhiwen Cao, Yufei Chen, Chengcan Yang, Bing Wang, Yunqi Li, Bin Li, Yufang Bi, Guang Ning, Jiqiu Wang, Weiqing Wang, Ruixin Liu   +16 more
wiley   +1 more source

DNA polymerase zeta can efficiently replicate structures formed by AT/TA repeat sequences and prevent their deletion. [PDF]

Nucleic Acids Res
Das M, Hile SE, Brewster J, Boer JL, Bezalel-Buch R, Guo Q, Yang W, Burgers PM, Eckert KA, Freudenreich CH.   +9 more
europepmc   +1 more source

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

Advanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi, Kai Tao, Xiaomin Wen, Dayun Feng, Zifan Mai, Hui Ding, Honghui Mao, Mingming Wang, Qian Yang, Jie Xiang, Jie Zhang, Shengxi Wu   +11 more
wiley   +1 more source

Pathogen-encoded Rum DNA polymerase drives rapid bacterial drug resistance. [PDF]

Nucleic Acids Res
Jaszczur MM, Pham P, Ojha D, Pham CQ, McDonald JP, Woodgate R, Goodman MF.   +6 more
europepmc   +1 more source