Results 211 to 220 of about 954,914 (266)

DNA‐Dependent DNA Polymerases

Current Protocols in Molecular Biology, 2008
AbstractThis unit presents characteristics and reaction conditions of the DNA‐dependent DNA polymerases, including E. coli DNA polymerase I and its Klenow fragment, T4 DNA polymerase, native and modified T7 DNA polymerase, phi29 DNA polymerase, Bst DNA polymerase, and Taq DNA polymerase. The unit also provides overviews of other classes of thermophilic
Rebecca B, Kucera, Nicole M, Nichols
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Database of DNA Polymerases

Current Protocols in Molecular Biology, 2012
AbstractThe DNA Polymerase Database (Polbase) is intended to compile the wealth of existing DNA polymerase information from public and private records into an open, searchable database. Curr. Protoc. Mol. Biol. 99:3.25.1‐3.25.2. © 2012 by John Wiley & Sons, Inc.
Bradley W, Langhorst, Nicole M, Nichols
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Eukaryotic DNA polymerases

Current Opinion in Structural Biology, 2018
The eukaryotic DNA replication machinery is conserved from yeast to humans and requires the actions of multiple DNA polymerases. In addition to replicative DNA polymerases for duplication of the leading and lagging DNA strands, another group of specialized polymerases is required for DNA repair and/or translesion DNA synthesis (TLS).
Rinku, Jain   +2 more
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DNA Polymerase II

Nature, 1970
A membrane associated DNA polymerizing enzyme has been solubilized, partially isolated and characterized.
openaire   +3 more sources

DNA polymerases and carcinogenesis

Biochemistry (Moscow), 2010
There are many various chromosomal and gene mutations in human cancer cells. The total mutation rate in normal human cells is 2·10(-7) mutations/gene/division. From 6 to 12 carcinogenic mutations can arise by the end of the life, and these can affect the structure of ~150 protooncogenes and genes encoding suppressors of tumor growth. However, this does
V M, Krutyakov, T P, Kravetskaya
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ZINC in DNA polymerases

Biochemical and Biophysical Research Communications, 1971
Summary Homogeneous DNA polymerases from E. coli and sea urchins contain zinc in a proportion of approximately 2 and 4 gm atoms Zn/mole enzyme respectively. Specific inhibition of the enzyme by ortho -phenanthroline and lack of inhibition by meta -phenanthroline suggest that the bound zinc plays a functional role in the interaction of DNA with ...
J P, Slater, A S, Mildvan, L A, Loeb
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Thermostable DNA Polymerases

1996
Publisher Summary This chapter describes DNA polymerases of mesophiles and covers DNA polymerases of thermophilic Eubacteria and Archaea. It covers both thermophiles, organisms that grow optimally in the range of 50–70oC, but not at 90oC, and hyperthermophiles, organisms with an optimal growth temperature of at least 80°C, which also grow at 90°C ...
F B, Perler, S, Kumar, H, Kong
openaire   +5 more sources

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