Results 231 to 240 of about 1,506,691 (357)
Advanced Science, EarlyView.Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater +13 more
wiley +1 more source
Involvement of DNA polymerase alpha in simian virus 40 DNA replication.
, 1978 Howard J. Edenberg +2 more
openalex +1 more source
Component E of the DNA‐Dependent RNA Polymerase of the Archaebacterium Thermoplasma acidophilum Is Required for the Transcription of Native DNA [PDF]
, 1982 Ralf Schnabel +2 more
openalex +1 more source
DNA polymerase λ autoinhibition is relieved via Ku interaction during non-homologous end joining. [PDF]
Nucleic Acids ResCase BC, Scoccia L, Zhao Z, Loparo JJ.
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein. [PDF]
Nat CommunKeskitalo S +10 more
europepmc +1 more source
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source