Results 221 to 230 of about 954,914 (266)
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Nature, 1974
DNA polymerase has been isolated from the cytoplasm of several mammalian tissues as well as several cell lines in culture1–8. This has been puzzling because DNA replication and repair are processes generally believed to be restricted to the nucleus, where chromatin is located.
J J, Byrnes +3 more
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DNA polymerase has been isolated from the cytoplasm of several mammalian tissues as well as several cell lines in culture1–8. This has been puzzling because DNA replication and repair are processes generally believed to be restricted to the nucleus, where chromatin is located.
J J, Byrnes +3 more
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Biochemical and Biophysical Research Communications, 1965
Abstract An experiment will be described which shows that DNA polymerase helps select the base in DNA replication. After elucidating the structure of DNA (1953a), Watson and Crick proposed a template mechanism for the replication of DNA (1953b).
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Abstract An experiment will be described which shows that DNA polymerase helps select the base in DNA replication. After elucidating the structure of DNA (1953a), Watson and Crick proposed a template mechanism for the replication of DNA (1953b).
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2012
DNA polymerase ε (Pol ε) is one of three replicative DNA polymerases in eukaryotic cells. Pol ε is a multi-subunit DNA polymerase with many functions. For example, recent studies in yeast have suggested that Pol ε is essential during the initiation of DNA replication and also participates during leading strand synthesis.
Matthew, Hogg, Erik, Johansson
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DNA polymerase ε (Pol ε) is one of three replicative DNA polymerases in eukaryotic cells. Pol ε is a multi-subunit DNA polymerase with many functions. For example, recent studies in yeast have suggested that Pol ε is essential during the initiation of DNA replication and also participates during leading strand synthesis.
Matthew, Hogg, Erik, Johansson
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Annual Review of Biochemistry, 1977
PERSPECTIVES A ND SU MMARY ......... 25 IN TR ODUCTION ........ ... 27 CE LLU LAR DNA POL YMERASES ....... . 28 DNA Polymerase a ......... 28 DNA Polymerase /3 31 DNA Polymerase 'Y •.....• • 33 Mitochondrial DNA Polymerase .... ......... 34 VIR US-INDUCED DNA POL YMERASES ......... ....
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PERSPECTIVES A ND SU MMARY ......... 25 IN TR ODUCTION ........ ... 27 CE LLU LAR DNA POL YMERASES ....... . 28 DNA Polymerase a ......... 28 DNA Polymerase /3 31 DNA Polymerase 'Y •.....• • 33 Mitochondrial DNA Polymerase .... ......... 34 VIR US-INDUCED DNA POL YMERASES ......... ....
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2004
Publisher Summary This chapter focuses on DNA polymerases (Pols) and their functions. DNA Pols are central players in DNA repair and replication—the processes that duplicate genomes and maintain their integrity to ensure faithful transmission of genetic information from one generation to other.
Katarzyna, Bebenek, Thomas A, Kunkel
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Publisher Summary This chapter focuses on DNA polymerases (Pols) and their functions. DNA Pols are central players in DNA repair and replication—the processes that duplicate genomes and maintain their integrity to ensure faithful transmission of genetic information from one generation to other.
Katarzyna, Bebenek, Thomas A, Kunkel
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Nature, 1968
EVIDENCE which has accumulated over the past decade from mammalian and non-mammalian sources about the enzyme(s) involved in DNA synthesis has indicated the possibility of a multiunit structure for this enzyme. Mammalian DNA polymerase DNA nucleotidyl-transferase (E.G.2.7.7.7) was first isolated from a high speed supernatant fraction of cell ...
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EVIDENCE which has accumulated over the past decade from mammalian and non-mammalian sources about the enzyme(s) involved in DNA synthesis has indicated the possibility of a multiunit structure for this enzyme. Mammalian DNA polymerase DNA nucleotidyl-transferase (E.G.2.7.7.7) was first isolated from a high speed supernatant fraction of cell ...
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1975
Publisher Summary This chapter states that physiological experiments demonstrating variations of DNA polymerase activities were first done in mammalian systems, whereas the first relevant genetic experiments in bacteria came 12 years after the discovery of Escherichia coli DNA polymerase I.
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Publisher Summary This chapter states that physiological experiments demonstrating variations of DNA polymerase activities were first done in mammalian systems, whereas the first relevant genetic experiments in bacteria came 12 years after the discovery of Escherichia coli DNA polymerase I.
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Annals of the New York Academy of Sciences, 1992
K C, Sitney, M E, Budd, J L, Campbell
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K C, Sitney, M E, Budd, J L, Campbell
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