Results 61 to 70 of about 1,931,156 (311)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Phylogenetic analysis of Badrashbu species using DNA polymorphism
Journal of Medicinal Plants, 2005 Background: The name “badrashbu” has been applied to some species of Dracocephalum (Labiatae) in Iran. Dracocephalum kotschyi is an indigenous herbaceous plant, used in folk medicine as a flavor in Iran. D.
S Saeidnia +4 more
doaj
Czech Journal of Genetics and Plant BreedingThe genus Solanum comprises numerous wild and cultivated species that are important for potato breeding. This pilot-scale study aimed to evaluate the genetic diversity in 44 accessions from Solanum sect. Petota, comprising wild species, Andean landraces,
Zuzana Rottová +5 more
doaj +1 more source
XRCC-1 Gene Polymorphism (Arg399Gln) and Susceptibility to Development of Lung Cancer in Cohort of North Indian Population: A Pilot Study [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Smoking has been considered to be the major cause of lung cancer. However, only a fraction of cigarette smokers develop this disease.
Vibha Uppal +4 more
doaj +1 more source
Statistical analysis of DNA polymorphism
Genes & Genetic Systems, 1993 A large amount of genetic variation can be maintained in natural populations. In order to understand the mechanism maintaining genetic variation, we must first estimate the amount of genetic variation. There are two measures for estimating the amount of DNA polymorphism, i.e., the average number of pairwise nucleotide differences and the number of ...
openaire +3 more sources
Molecular genetic studies on Brassica napus L. [PDF]
, 1991 The feasibility of using two different methods of assaying for DNA polymer phisms has been assessed. They were Restriction fragment length polymorphisms (RFLPs) as revealed by a range of characterised Brassica cDNA sequences and Random amplified ...
Napis, Suhaimi, Napis, S
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA. [PDF]
PLoS ONE, 2012 BACKGROUND: Plasma DNA obtained from a pregnant woman contains a mixture of maternal and fetal DNA. The fetal DNA proportion in maternal plasma is relatively consistent as determined using polymorphic genetic markers across different chromosomes in ...
Gary J W Liao +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Atom Indonesia, 2018 The genetic polymorphism of DNA repair gene plays some important role in regulating individual sensitivity to ionizing radiation, maintaining DNA integrity, and preventing cancer and DNA damage.XRCC1 as one of the members ofbase excision repair (BER) is ...
H. N.E. Surniyantoro +5 more
doaj +1 more source