Results 261 to 270 of about 225,059 (304)

DNA REPAIR ENZYMES

Annual Review of Biochemistry, 1988
DIRECT REPAIR: DNA PHOTOLYASES.. . . . ......... . ......... 31 Escherichia Coli Photolyase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . 31 Saccharomyces Cerevisiae Photolyase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
A, Sancar, G B, Sancar
openaire   +3 more sources

DNA Tile Self‐Assembly Guided by Base Excision Repair Enzymes [PDF]

Angewandte Chemie - International Edition, 2022
We demonstrate here the use of DNA repair enzymes to control the assembly of DNA-based structures. To do so, we employed uracil-DNA glycosylase (UDG) and formamidopyrimidine DNA glycosylase (Fpg), two enzymes involved in the base excision repair (BER ...
Nada Farag, Gianfranco Ercolani, Erica Del Grosso   +2 more
exaly   +2 more sources

"Active" photoprotection: sunscreens with DNA repair enzymes [PDF]

Italian Journal of Dermatology and Venereology, 2017
Ultraviolet (UV) radiation exerts different harmful effects on human health, being the main etiological agent of certain skin cancers and photoaging. In this context, photoprotection, intended as a set of measures adopted to limit and prevent the effects of UV radiation, plays a critical role in avoiding undesired sunlight outcomes.
Megna, Matteo, Lembo, Serena, Balato, Nicola, Monfrecola, Giuseppe   +3 more
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DNA Repair Enzymes

Current Protocols in Molecular Biology, 2008
AbstractIn vivo DNA damage impacts the genetic stability of an organism; therefore, multiple pathways utilizing a large number of enzymes have evolved to repair DNA damage. This unit focuses on enzymes involved in base excision repair (BER). The BER enzymes possessing N‐glycosylase activity can find and remove a wide variety of damaged bases in a sea ...
Thomas C, Evans, Nicole M, Nichols
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Tuberin regulates the DNA repair enzyme OGG1

American Journal of Physiology-Renal Physiology, 2008
The tuberous sclerosis complex (TSC) is caused by defects in one of two tumor suppressor genes, TSC-1 or TSC-2. The TSC-2 gene encodes tuberin, a protein involved in the pathogenesis of kidney tumors, both angiomyolipomas and renal cell carcinomas. We investigated a potential role for tuberin in regulating a key DNA repair pathway.
Samy L, Habib, Daniel J, Riley, Lenin, Mahimainathan, Basant, Bhandari, Goutam Ghosh, Choudhury, Hanna E, Abboud   +5 more
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Aberrant activity of the DNA repair enzyme AlkB

Journal of Inorganic Biochemistry, 2004
Escherichia coli AlkB is a DNA/RNA repair enzyme containing a mononuclear Fe(II) site that couples the oxidative decomposition of alpha-ketoglutarate (alphaKG) to the hydroxylation of 1-methyladenine or 3-methylcytosine lesions in DNA or RNA, resulting in release of formaldehyde and restoration of the normal bases.
Timothy F, Henshaw, Michael, Feig, Robert P, Hausinger   +2 more
openaire   +2 more sources

Lymphocyte DNA adducts and polymorphism in the DNA repair enzyme XPD

Biomarkers, 2001
The effect of genetic polymorphism of DNA repair enzyme on the DNA adduct levels was evaluated in this study. We explored the relationship between polymorphism in the nucleotide excision repair enzyme XPD and DNA adduct levels in lymphocytes. Lymphocyte DNA adducts were measured by a (32.)
M, Ichiba, J, Zhang, C, Kiyohara, Y, Nakanishi, K, Takayama, N, Hara, M, Enoki, K, Tomokuni   +7 more
openaire   +2 more sources

Enzymes involved in the repair of damaged DNA

Archives of Biochemistry and Biophysics, 1981
The progress that has been made in our understanding of the enzymatic mechanisms by which modified nucleotides in DNA are recognized and repaired is due, in part, to the developments that have been made in photobiology and photochemistry. It was these areas of activity that led to the identification of the primary ultraviolet irradiation photoproducts ...
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Detection of DNA point mutations with DNA mismatch repair enzymes

Carcinogenesis, 1994
We have developed a simple and reliable procedure to screen gene mutations using DNA mismatch repair (MR) specific mut Y enzyme of Escherichia coli and thymidine DNA glycosylase from HeLa cells. The mut Y enzyme cleaves A of G/A mismatches in DNA duplex and thymidine glycosylase cleaves T at G/T mismatches.
I C, Hsu, Q, Yang, M W, Kahng, J F, Xu
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Death of an enzyme: suicide repair of DNA

Trends in Biochemical Sciences, 1983
Abstract Alkylation of DNA forms lethal and mutagenic lesions, most of which are repaired by conventional enzymes. A unique activity has been discovered which corrects an important mutagenic adduct in one step, by a self-destructive mechanism.
Bruce Demple, Peter Karran
openaire   +1 more source