Results 221 to 230 of about 178,865 (248)
Some of the next articles are maybe not open access.
Initiation of DNA replication in yeast chromosomes
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1987Abstract A family of DNA fragments from the yeast genome has properties that suggest that chromosome replication starts at specific DNA sequences. These elements (autonomously replicating sequences: ARS) have a bipartite structure: a small (less than 20 base pairs) AT-rich region essential for function, flanked by larger regions ...
openaire +2 more sources
Initiation of DNA replication in eukaryotic chromosomes
Journal of Cellular Biochemistry, 1998Our understanding of the process by which eukaryotes regulate initiation of DNA replication has made remarkable advances in the past few years, thanks in large part to the explosion of genetic and biochemical information on the budding yeast, Saccharomyces cerevisiae.
openaire +3 more sources
Evidence for “the Wedge”, Initiator of DNA Replication
Nature, 1970A low molecular weight factor from ascitic fluid stimulates DNA replication—especially with double stranded DNA as template—and cell division. Its properties are those which would be expected of “the wedge”, a protein thought to be essential for the organization and action of DNA polymerase.
S, Erhan +4 more
openaire +2 more sources
Kinetics of adenovirus dna replication II. Initiation of adenovirus DNA replication
Virology, 1980Abstract We have developed three methods to estimate the initiation of adenovirus DNA replication: (a) direct measurement during density-shift experiments, (b) calculation using the saturation kinetics of viral DNA accumulation, and (c) calculation using the steady-state kinetics of viral DNA replication.
J W, Bodnar, G D, Pearson
openaire +2 more sources
Initiation of DNA replication in human chromosomes
Experimental Cell Research, 1977Abstract DNA replication within the first 10 min of the S phase was studied using synchronized human diploid cells. It appeared that every chromosome in the human genome, including late-replicating X, had segment(s) which initiated DNA replication within the first 10 min of the S phase.
openaire +2 more sources
Cdt1 and Geminin in DNA Replication Initiation
2012One of the mechanisms controlling the initiation of DNA replication is the dynamic interaction between Cdt1, which promotes assembly of the pre-replication license complex, and Geminin, which inhibits it. Specifically, Cdt1 cooperates with the cell cycle protein Cdc6 to promote loading of the minichromosome maintenance helicases (MCM) onto the ...
Christophe, Caillat +1 more
openaire +2 more sources
Regulation of eukaryotic DNA replication at the initiation step
Biochemical Society Transactions, 2003The studies of cell growth and division have remained at the centre of biomedical research for more than 100 years. The combination of genetic, biochemical, molecular and cell biological techniques recently yielded a burst in what is known of the molecular control of cell growth processes.
Pollok, S. +4 more
openaire +2 more sources
Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
Molecular Cell, 2021Manzar Hossain +2 more
exaly
Multiple mechanisms for overcoming lethal over‐initiation of DNA replication
Molecular Microbiology, 2022Mary E Anderson +2 more
exaly