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An enhancement of extrachromosomal circular DNA enrichment and amplification to address the extremely low overlap between replicates. [PDF]
Burnham CM +6 more
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Bacterial restriction-modification systems: mechanisms of defense against phage infection. [PDF]
Kang H, Gao A, Zhu Y.
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Plasmid Curing of <i>Pseudoalteromonas haloplanktis</i> TAC125 Using Homologous Recombination and PTasRNA Gene Silencing. [PDF]
Severino A +4 more
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ΔNp63α drives serine synthesis to promote carboplatin resistance in NSCLC. [PDF]
Deng L +6 more
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5mC and 6mA DNA Methylation in the Fungal Kingdom: From Genome Defense to Epigenetic Regulation. [PDF]
Malyshev DP +5 more
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Correction to "Homosalate Boosts the Release of Tumour-derived Extracellular Vesicles With Protection Against Anchorage-Loss Property". [PDF]
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Programmable DNA-Guided Artificial Restriction Enzymes
ACS Synthetic Biology, 2017Restriction enzymes are essential tools for recombinant DNA technology that have revolutionized modern biological research. However, they have limited sequence specificity and availability. Here we report a Pyrococcus furiosus Argonaute (PfAgo) based platform for generating artificial restriction enzymes (AREs) capable of recognizing and cleaving DNA ...
Huimin Zhao, Behnam Enghiad
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