Advances in Diversity, Evolutionary Dynamics and Biotechnological Potential of Restriction-Modification Systems. [PDF]
Chen C, Zhang Y, Wu H, Qiao J, Caiyin Q.
europepmc +1 more source
Real-time observation of DNA looping dynamics of Type IIE restriction enzymes NaeI and NarI [PDF]
Bram van den Broek+4 more
openalex +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Methionine Restriction Differentially Modulates Expression of Genes in the Base Excision Repair Pathway in Rat Brain and Liver. [PDF]
Gredilla R+2 more
europepmc +1 more source
DNA sequencing analysis of several G6PD variants previously defined by PCR-restriction enzyme analysis [PDF]
Gerardo Vaca, Eliakym Arámbula‐Meraz
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A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
PCR-RFLP assays to detect recessive lethal alleles in Landrace and Duroc pigs in Vietnam. [PDF]
Bui APN, Nguyen NM, Le Q.
europepmc +1 more source
DNA Sequence Modulates the Conformation of the Food Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the Recognition Sequence of the NarI Restriction Enzyme, [PDF]
Feng Wang+4 more
openalex +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source