Results 241 to 250 of about 397,727 (310)

Plasmid2MC: efficient cell-free generation of high-purity minicircle DNA for genome editing in mammalian cells. [PDF]

Commun Biol
Oliynyk RT, Mahas A, Karpinski E, Church GM.   +3 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Fueling the Fire: How Glutamine Metabolism Sustains Leukemia Growth and Resistance. [PDF]

BioMed (Basel)
Silvestri G.
europepmc   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Hypoxia Preserves Chromatin Integrity and Delays Cellular Senescence through Epigenetic Regulation. [PDF]

Biomol Ther (Seoul)
Park C, Park H.
europepmc   +1 more source

Workflow for Gene Overexpression and Phenotypic Characterisation in <i>Taraxacum kok-saghyz</i>. [PDF]

Methods Protoc
Lopez L, Savoia MA, Daddiego L, Facella P, Fantini E, Bianco L, Maci S, Panara F.   +7 more
europepmc   +1 more source

Identification of an in-frame insertion in ACKR1 in five individuals from Agri community, India. [PDF]

Hematol Transfus Cell Ther
Roshan S, Prakash S, Kanjaksha G, Ajit G.   +3 more
europepmc   +1 more source

Genome minimization of a Burkholderia bacterial host. [PDF]

Metab Eng
Paulo BS, Romanowski SB, Kadjo AE, Lourenzon VB, Eustáquio AS.   +4 more
europepmc   +1 more source

Diffdigester.uni-jena.de: a tool for optimized selection of restriction enzymes for plasmid identification in cloning procedures. [PDF]

Nucleic Acids Res
Gühmann M, Reuter S, Mrowka R.
europepmc   +1 more source