Results 161 to 170 of about 2,690,595 (341)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution. [PDF]

Nat Methods
Hingerl JC, Martens LD, Karollus A, Manz T, Buenrostro JD, Theis FJ, Gagneur J.   +6 more
europepmc   +2 more sources

Molecular Phylogeny of Asian Freshwater and Marine Stingrays Based on the DNA Nucleotide and Deduced Amino Acid Sequences of the Cytochrome <i>b</i> Gene

, 1999
Keijiro Sezaki, Rowshan Ara Begum, P. Wongrat, Mansha Prasad Srivastava, Sachi SriKantha, Kiyoshi Kikuchi, Hajime Ishihara, S. Tanaka, Tōru Taniuchi, Shugo Watabe   +9 more
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Short CommunicationNew insights into telomeric DNA sequence (TTAGGG)n location in bat chromosomes

, 2009
K.C. Faria, S.R.C. Marchesin, P.R.L. Moreira, Mateus R. Beguelini, Eliana Morielle‐Versute   +4 more
openalex   +1 more source

Evolutionary analyses of DNA sequences subject to constraints of secondary structure. [PDF]

, 1995
Spencer V. Muse
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

gReLU: a comprehensive framework for DNA sequence modeling and design. [PDF]

Nat Methods
Lal A, Gunsalus L, Nair S, Biancalani T, Eraslan G.   +4 more
europepmc   +1 more source

DNA isolation and optimization of sequence-related amplified polymorphism-polymerase chain reaction (SRAP-PCR) condition for endangered Polyporus umbellatus

, 2011
Yuejin Zhang
openalex   +1 more source

ProteDNA: a sequence-based predictor of sequence-specific DNA-binding residues in transcription factors [PDF]

, 2009
Wenyi Chu, Yu‐Feng Huang, Chun-Chin Huang, Yi‐Sheng Cheng, Chien‐Kang Huang, Yen‐Jen Oyang   +5 more
openalex   +1 more source