Results 171 to 180 of about 2,690,595 (341)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Search-and-remove genome editing allows selection of cells by DNA sequence. [PDF]
Nat CommunFast L +7 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
DVOUG enables robust DNA sequence assembly and reconstruction with a dynamic, variable-order graph. [PDF]
Cell Rep MethodsLiu Z +7 more
europepmc +1 more source
How Evolution of Genomes Is Reflected in Exact DNA Sequence Match Statistics [PDF]
, 2014 Florian Massip +3 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Common DNA sequence variation influences epigenetic aging in African populations. [PDF]
Commun BiolMeeks GL +9 more
europepmc +1 more source