Results 1 to 10 of about 1,188,779 (225)

435 Age-dependent Regulation of Follicle-Stimulating Hormone N-glycosylation in Female Gonadotrope Cells

open access: yesJournal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: Age-specific N-glycosylation occurs on follicle- stimulating hormone (FSH) in pituitaries of post-menopausal women and results in a higher ratio of fully glycosylated to hypoglycosylated FSH.
Rosemary McDonald   +4 more
doaj   +1 more source

Relationships of gut microbiota, short-chain fatty acids, inflammation, and the gut barrier in Parkinson’s disease

open access: yesMolecular Neurodegeneration, 2021
Background Previous studies have reported that gut microbiota, permeability, short-chain fatty acids (SCFAs), and inflammation are altered in Parkinson’s disease (PD), but how these factors are linked and how they contribute to disease processes and ...
Velma T. E. Aho   +9 more
doaj   +1 more source

Comparative genomic analysis of two ST320 Streptococcus pneumoniae isolates, representing serotypes 19A and 19F

open access: yesBMC Genomic Data, 2023
Background Streptococcus pneumoniae (pneumococcus) represents an important human pathogen, responsible for respiratory and invasive infections in the community.
Weronika Puzia   +4 more
doaj   +1 more source

Multiomics implicate gut microbiota in altered lipid and energy metabolism in Parkinson’s disease

open access: yesnpj Parkinson's Disease, 2022
We aimed to investigate the link between serum metabolites, gut bacterial community composition, and clinical variables in Parkinson’s disease (PD) and healthy control subjects (HC).
Pedro A. B. Pereira   +6 more
doaj   +1 more source

Comparison of mitochondrial DNA sequences from whole blood and lymphoblastoid cell lines

open access: yesScientific Reports, 2022
Lymphoblastoid cell lines (LCLs) provide an unlimited source of genomic DNA for genetic studies. Here, we compared mtDNA sequence variants, heteroplasmic or homplasmic, between LCL (sequenced by mitoRCA-seq method) and whole blood samples (sequenced ...
Chunyu Liu   +8 more
doaj   +1 more source

Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification

open access: yesBMC Medical Genomics, 2021
Background Coronary artery calcification (CAC) is a noninvasive measure of coronary atherosclerosis, the proximal pathophysiology underlying most cases of myocardial infarction (MI). We sought to identify expression signatures of early MI and subclinical
Xiaoling Zhang   +13 more
doaj   +1 more source

IMG-DNA: Approximate DNA Storage for Images [PDF]

open access: yes, 2021
Deoxyribonucleic Acid (DNA) as a storage medium with high density and long-term preservation properties can satisfy the requirement of archival storage for rapidly increased digital volume. The read and write processes of DNA storage are error-prone. Images widely used in social media have the properties of fault tolerance which are well fitted to the ...
arxiv   +1 more source

Highly Resistant Serotype 19A Streptococcus pneumoniae of the GPSC1/CC320 Clone from Invasive Infections in Poland Prior to Antipneumococcal Vaccination of Children

open access: yesInfectious Diseases and Therapy, 2023
Introduction The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced the number of pneumococcal infections.
Weronika Puzia   +9 more
doaj   +1 more source

BARCOSEL: a tool for selecting an optimal barcode set for high-throughput sequencing

open access: yesBMC Bioinformatics, 2018
Background Current high-throughput sequencing platforms provide capacity to sequence multiple samples in parallel. Different samples are labeled by attaching a short sample specific nucleotide sequence, barcode, to each DNA molecule prior pooling them ...
Panu Somervuo   +5 more
doaj   +1 more source

Case Report of COVID-19 after Full Vaccination: Viral Loads and Anti-SARS-CoV-2 Antibodies

open access: yesDiagnostics, 2021
The introduction of effective vaccines against SARS-CoV-2 is expected to prevent COVID-19. However, sporadic cases of infection in vaccinated persons have been reported. We describe a case of a double-dose vaccinated woman with COVID-19.
Magdalena Komiazyk   +5 more
doaj   +1 more source

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