Results 1 to 10 of about 1,871,571 (343)
Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing [PDF]
Jagadish P. Hazra +10 more
openalex +2 more sources
Illuminating Choices for Library Prep: A Comparison of Library Preparation Methods for Whole Genome Sequencing of Cryptococcus neoformans Using Illumina HiSeq. [PDF]
, 2014 The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the major sequencing technology companies annually.
A Adey +18 more
core +15 more sources
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: Age-specific N-glycosylation occurs on follicle- stimulating hormone (FSH) in pituitaries of post-menopausal women and results in a higher ratio of fully glycosylated to hypoglycosylated FSH.
Rosemary McDonald +4 more
doaj +1 more source
Molecular Neurodegeneration, 2021 Background Previous studies have reported that gut microbiota, permeability, short-chain fatty acids (SCFAs), and inflammation are altered in Parkinson’s disease (PD), but how these factors are linked and how they contribute to disease processes and ...
Velma T. E. Aho +9 more
doaj +1 more source
BMC Genomic Data, 2023 Background Streptococcus pneumoniae (pneumococcus) represents an important human pathogen, responsible for respiratory and invasive infections in the community.
Weronika Puzia +4 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2022 With the aim of expediting drug target discovery and validation for respiratory diseases, we developed an optimized method for in situ somatic gene disruption in murine lung epithelial cells via AAV6-mediated CRISPR-Cas9 delivery.
Honglin Chen +13 more
doaj +1 more source
Exoquence DNA sequencing [PDF]
Nucleic Acids Research, 1993 We have developed a strategy for DNA sequencing based on exonuclease III digestion followed by double strand specific endonuclease digestion and direct dideoxynucleotide sequencing reaction. This strategy eliminates the need for subcloning, oligonucleotide primers, and prior knowledge of the DNA to be sequenced.
C, Li, P W, Tucker
openaire +2 more sources
Culture-Negative Subacute Lactobacillus Endocarditis Diagnosed by Microbial Cell-Free DNA Sequencing [PDF]
JACC Case RepAbduljabar Adi +4 more
openalex +2 more sources
Multiomics implicate gut microbiota in altered lipid and energy metabolism in Parkinson’s disease
npj Parkinson's Disease, 2022 We aimed to investigate the link between serum metabolites, gut bacterial community composition, and clinical variables in Parkinson’s disease (PD) and healthy control subjects (HC).
Pedro A. B. Pereira +6 more
doaj +1 more source
Comparison of mitochondrial DNA sequences from whole blood and lymphoblastoid cell lines
Scientific Reports, 2022 Lymphoblastoid cell lines (LCLs) provide an unlimited source of genomic DNA for genetic studies. Here, we compared mtDNA sequence variants, heteroplasmic or homplasmic, between LCL (sequenced by mitoRCA-seq method) and whole blood samples (sequenced ...
Chunyu Liu +8 more
doaj +1 more source