Results 1 to 10 of about 1,837,634 (299)
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: Age-specific N-glycosylation occurs on follicle- stimulating hormone (FSH) in pituitaries of post-menopausal women and results in a higher ratio of fully glycosylated to hypoglycosylated FSH.
Rosemary McDonald +4 more
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Molecular Neurodegeneration, 2021 Background Previous studies have reported that gut microbiota, permeability, short-chain fatty acids (SCFAs), and inflammation are altered in Parkinson’s disease (PD), but how these factors are linked and how they contribute to disease processes and ...
Velma T. E. Aho +9 more
doaj +1 more source
BMC Genomic Data, 2023 Background Streptococcus pneumoniae (pneumococcus) represents an important human pathogen, responsible for respiratory and invasive infections in the community.
Weronika Puzia +4 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2022 With the aim of expediting drug target discovery and validation for respiratory diseases, we developed an optimized method for in situ somatic gene disruption in murine lung epithelial cells via AAV6-mediated CRISPR-Cas9 delivery.
Honglin Chen +13 more
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Multiomics implicate gut microbiota in altered lipid and energy metabolism in Parkinson’s disease
npj Parkinson's Disease, 2022 We aimed to investigate the link between serum metabolites, gut bacterial community composition, and clinical variables in Parkinson’s disease (PD) and healthy control subjects (HC).
Pedro A. B. Pereira +6 more
doaj +1 more source
Culture-Negative Subacute Lactobacillus Endocarditis Diagnosed by Microbial Cell-Free DNA Sequencing. [PDF]
JACC Case RepAdi A +4 more
europepmc +2 more sources
Comparison of mitochondrial DNA sequences from whole blood and lymphoblastoid cell lines
Scientific Reports, 2022 Lymphoblastoid cell lines (LCLs) provide an unlimited source of genomic DNA for genetic studies. Here, we compared mtDNA sequence variants, heteroplasmic or homplasmic, between LCL (sequenced by mitoRCA-seq method) and whole blood samples (sequenced ...
Chunyu Liu +8 more
doaj +1 more source
BMC Medical Genomics, 2021 Background Coronary artery calcification (CAC) is a noninvasive measure of coronary atherosclerosis, the proximal pathophysiology underlying most cases of myocardial infarction (MI). We sought to identify expression signatures of early MI and subclinical
Xiaoling Zhang +13 more
doaj +1 more source
BARCOSEL: a tool for selecting an optimal barcode set for high-throughput sequencing
BMC Bioinformatics, 2018 Background Current high-throughput sequencing platforms provide capacity to sequence multiple samples in parallel. Different samples are labeled by attaching a short sample specific nucleotide sequence, barcode, to each DNA molecule prior pooling them ...
Panu Somervuo +5 more
doaj +1 more source
Infectious Diseases and Therapy, 2023 Introduction The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced the number of pneumococcal infections.
Weronika Puzia +9 more
doaj +1 more source