Results 111 to 120 of about 1,188,878 (324)
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Sequencing of Genomic DNA [PDF]
BioTechniques, 1999 Ulrich Mahlknecht +2 more
openaire +4 more sources
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
Sensing DNA - DNA as nanosensor: a perspective towards nanobiotechnology [PDF]
arXiv, 2005 Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA may be used as a local sensor.
arxiv
Apple II software for M13 shotgun DNA sequencing [PDF]
, 1982 Roger Larson, Joachim Messing
openalex +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Dy-mer: An Explainable DNA Sequence Representation Scheme using Sparse Recovery [PDF]
arXivDNA sequences encode vital genetic and biological information, yet these unfixed-length sequences cannot serve as the input of common data mining algorithms. Hence, various representation schemes have been developed to transform DNA sequences into fixed-length numerical representations.
arxiv
Identify the stiffness of DNA via deep learning [PDF]
arXiv, 2019 DNA detection is of great significance in the point-of-care diagnostics. The stiffness of DNA, varying with its sequence and mechanochemical environment, could be a potential marker for DNA identification. The steric configurations of DNA fragments with different stiffness were simulated by employing the Kirchhoff theory of thin elastic rods.
arxiv
Tn5supF, a 264-base-pair transposon derived from Tn5 for insertion mutagenesis and sequencing DNAs cloned in phage lambda. [PDF]
, 1989 Suhas H. Phadnis +2 more
openalex +1 more source