Results 241 to 250 of about 3,677,492 (346)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

DNA sequencing in oncology: a focus group study on a duty to recontact. [PDF]

Future Sci OA
Giesbertz NAA, Assen LS, van Harten WH, Bredenoord AL.   +3 more
europepmc   +1 more source

High‐Throughput DNA sequencing of ancient wood

Molecular Ecology, 2018
S. Wagner, Frédéric Lagane, Andaine Seguin-Orlando, Mikkel Schubert, Thibault Leroy, E. Guichoux, É. Chancerel, Inger Bech-Hebelstrup, Vincent Bernard, Cyrille Billard, Yves Billaud, M. Bolliger, Christophe Croutsch, K. Čufar, F. Eynaud, K. Heussner, Joachim Köninger, Fabien Langenegger, F. Leroy, Christine Lima, N. Martinelli, G. Momber, A. Billamboz, O. Nelle, A. Palomo, R. Piqué, Marianne Ramstein, Roswitha Schweichel, H. Stäuble, Willy Tegel, X. Terradas, Florence Verdin, C. Plomion, A. Kremer, L. Orlando   +34 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Combining face-to-face laboratory sessions and a computer simulation effectively teaches gene editing and DNA sequencing to undergraduate genetics students. [PDF]

Biochem Mol Biol Educ
Vedova CD, Denyer G, Costabile M.
europepmc   +1 more source

High-resolution, strand-specific R-loop mapping via S9.6-based DNA–RNA immunoprecipitation and high-throughput sequencing

Nature Protocols, 2019
L. Sanz, F. Chédin
semanticscholar   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Molecular Classification of Endometrial Cancers Using an Integrative DNA Sequencing Panel. [PDF]

J Surg Oncol
Kim SR, Oldfield L, Kim RH, Espin-Garcia O, Han K, Vicus D, Eiriksson L, Tone A, Pollett A, Cesari M, Clarke B, Bernardini MQ, Pugh TJ, Ferguson SE.   +13 more
europepmc   +1 more source

DNA sequencing by hybridization: 100 bases read by a non-gel-based method.

, 1991
Žaklina Strezoska, Tatjana Paunesku, D Radosavljević, Ivan Labat, Radoje Drmanac, Radomir Crkvenjakov   +5 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source