Results 251 to 260 of about 1,871,571 (343)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Targeted Next-Generation Sequencing of Cell-Free DNA to Detect MYC -Immunoglobulin Translocation and Epstein-Barr Virus DNA in Plasma of Burkitt Lymphoma Patients in East Africa

Clara Chamba, Daisy Jennings, Rehema Shungu, Heavenlight Christopher, Emmanuel Josephat, Kieran Howard, Hélène Dreau, Adam Burns, William Frank Mawalla, Priscus Mapendo, Leah Mnango, Ismail D. Legason, Edrick Elias, Caroline Achola, Anthony Cutts, Emmanuel Balandya, Anna Schuh, Jacqueline Kamanga, Kristin Schroeder, Paul Ntemi, Julius Sseruyange, Alisen Ayitwala, Alex Mremi, Atukuzwe Kahakwa, Daniel Mbwambo, Elifuraha Mkwizu, Oliver Henke, Philomena Goodluck, Hadija Nabalende, Isaac Otim, Martin D. Ogwang, Pamela Atim, Erick Marogosa, Faraja Chiwanga, Godlove Sandi, Hadija Mwamtemi, Lulu Chirande, Patricia Scanlan, Salama Mahawi, George Mugambage Ruhago, Liberata Mwita, Malale Tungu, Raphael Zozimus Sangeda, Sam M. Mbulaiteye, Claire El Moulden, Dimitris Vavoulis, Jingjing Jiang, Kate Ridout, Laura Lopez Pascua, Liz Morrell, Mihaela Leonte, Sarah Wordsworth   +51 more
openalex   +1 more source

Exploring genetic diversity and population structure of Myanmar indigenous chickens using double digest restriction site-associated DNA sequencing. [PDF]

Anim Genet
Mon SLY, Lwin M, Maw AA, Htun LL, Bawm S, Nagano Y, Nagano AJ, Kawabe K, Wada Y, Okamoto S, Shimogiri T.   +10 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

DNA Sequence [PDF]

, 2020
openaire   +1 more source

DAGIP: alleviating cell-free DNA sequencing biases with optimal transport. [PDF]

Genome Biol
Passemiers A, Tuveri S, Jatsenko T, Vanderstichele A, Busschaert P, Coosemans A, Timmerman D, Tejpar S, Vandenberghe P, Lambrechts D, Raimondi D, Vermeesch JR, Moreau Y.   +12 more
europepmc   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Racial differences in endometrial cancer genomics and outcomes using UNCseq^TM targeted DNA sequencing. [PDF]

Gynecol Oncol Rep
Newton MA, Merker JD, Gong W, Patil S, Tan X, Cocoran DL, Pfefferle AD, Hayward MC, Broaddus R, Nichols HB, Olshan AF, Weissman B, Keku TO, Bae-Jump V.   +13 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source